Obsessive-compulsive disorder: puzzles and prospects

TW Robbins, MM Vaghi, P Banca - Neuron, 2019 - cell.com
Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

A fronto–striato–subthalamic–pallidal network for goal-directed and habitual inhibition

M Jahanshahi, I Obeso, JC Rothwell… - Nature Reviews …, 2015 - nature.com
Classically, the basal ganglia have been considered to have a role in producing habitual
and goal-directed behaviours. In this article, we review recent evidence that expands this …

Cortico-striatal-thalamic loop circuits of the orbitofrontal cortex: promising therapeutic targets in psychiatric illness

P Fettes, L Schulze, J Downar - Frontiers in systems neuroscience, 2017 - frontiersin.org
Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex
human behaviors such as evaluation, affect regulation and reward-based decision-making …

Structural and functional brain abnormalities in attention-deficit/hyperactivity disorder and obsessive-compulsive disorder: a comparative meta-analysis

LJ Norman, C Carlisi, S Lukito, H Hart… - JAMA …, 2016 - jamanetwork.com
Importance Patients with attention-deficit/hyperactivity disorder (ADHD) and obsessive-
compulsive disorder (OCD) share impaired inhibitory control. However, it is unknown …

Emotional processing in obsessive-compulsive disorder: a systematic review and meta-analysis of 25 functional neuroimaging studies

AL Thorsen, P Hagland, J Radua, D Mataix-Cols… - Biological Psychiatry …, 2018 - Elsevier
Background Patients with obsessive-compulsive disorder (OCD) experience aversive
emotions in response to obsessions, motivating avoidance and compulsive behaviors …

Habit formation

KS Smith, AM Graybiel - Dialogues in clinical neuroscience, 2016 - Taylor & Francis
Habits, both good ones and bad ones, are pervasive in animal behavior. Important
frameworks have been developed to understand habits through psychological and …

Biological markers for anxiety disorders, OCD and PTSD–a consensus statement. Part I: neuroimaging and genetics

B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2016 - Taylor & Francis
Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …

[PDF][PDF] Mapping compulsivity in the DSM-5 obsessive compulsive and related disorders: cognitive domains, neural circuitry, and treatment

NA Fineberg, AM Apergis-Schoute… - International Journal …, 2018 - academic.oup.com
Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm.
Growing evidence suggests that the neurocognitive mechanisms mediating behavioral …

The prefrontal cortex and OCD

SE Ahmari, SL Rauch - Neuropsychopharmacology, 2022 - nature.com
Abstract Obsessive Compulsive Disorder (OCD) is a highly prevalent and severe
neuropsychiatric disorder, with an incidence of 1.5–3% worldwide. However, despite the …

The junction between self and other? Temporo-parietal dysfunction in neuropsychiatry

CM Eddy - Neuropsychologia, 2016 - Elsevier
The temporo-parietal junction (TPJ) is implicated in a variety of processes including
multisensory integration, social cognition, sense of agency and stimulus-driven attention …