Melt extrusion with poorly soluble drugs–An integrated review

MA Repka, S Bandari, VR Kallakunta, AQ Vo… - International journal of …, 2018 - Elsevier
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …

Advances in terahertz time-domain spectroscopy of pharmaceutical solids: A review

P Bawuah, JA Zeitler - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
The rapid development of terahertz time-domain spectroscopy (THz-TDS) as a highly
versatile analytical tool for the characterisation of pharmaceutical materials has drawn …

Polymorphism in pharmaceutical solids

HG Brittain - Drugs and the pharmaceutical sciences, 1999 - api.taylorfrancis.com
It is now just about 10 years since the publication of the first edition of Polymorphism in
Pharmaceutical Solids, which certainly received a positive reaction from workers in drug …

Imaging with terahertz radiation

WL Chan, J Deibel, DM Mittleman - Reports on progress in …, 2007 - iopscience.iop.org
Within the last several years, the field of terahertz science and technology has changed
dramatically. Many new advances in the technology for generation, manipulation, and …

A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation

A Alzahrani, D Nyavanandi, P Mandati… - International Journal of …, 2022 - Elsevier
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …

An overview of recent studies on the analysis of pharmaceutical polymorphs

N Chieng, T Rades, J Aaltonen - Journal of pharmaceutical and biomedical …, 2011 - Elsevier
Pharmaceutical solids are well known to be able to exist in different solid-state forms and
there are a wide variety of solid-state analytical techniques available to characterize …

Terahertz pulsed spectroscopy and imaging in the pharmaceutical setting‐a review

JA Zeitler, PF Taday, DA Newnham… - Journal of Pharmacy …, 2007 - Wiley Online Library
Terahertz pulsed spectroscopy (TPS) and terahertz pulsed imaging (TPI) are two novel
techniques for the physical characterization of pharmaceutical drug materials and final solid …

Terahertz pulsed spectroscopy and imaging for pharmaceutical applications: A review

YC Shen - International journal of pharmaceutics, 2011 - Elsevier
The terahertz region of the electromagnetic spectrum spans the frequency range between
the infrared and the microwave. Traditionally the exploitation of this spectral region has been …

Perspectives on the amorphisation/milling relationship in pharmaceutical materials

M Descamps, JF Willart - Advanced Drug Delivery Reviews, 2016 - Elsevier
This paper presents an overview of recent advances in understanding the role of the
amorphous state in the physical and chemical transformations of pharmaceutical materials …

Investigating the function and design of molecular materials through terahertz vibrational spectroscopy

PA Banks, EM Kleist, MT Ruggiero - Nature Reviews Chemistry, 2023 - nature.com
Terahertz spectroscopy has proved to be an essential tool for the study of condensed phase
materials. Terahertz spectroscopy probes the low-frequency vibrational dynamics of atoms …