Intraportal islet transplantation: the impact of the liver microenvironment

V Delaune, T Berney, S Lacotte… - Transplant …, 2017 - Wiley Online Library
The portal vein remains the preferred site for pancreatic islet transplantation due to its easy
access and low morbidity. However, despite great progress in isolation and transplantation …

Advancements in innate immune regulation strategies in islet transplantation

K Duan, J Liu, J Zhang, T Chu, H Liu, F Lou… - Frontiers in …, 2024 - frontiersin.org
As a newly emerging organ transplantation technique, islet transplantation has shown the
advantages of minimal trauma and high safety since it was first carried out. The proposal of …

[图书][B] CPP, cell-penetrating peptides

Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

The impact of cell surface PEGylation and short-course immunotherapy on islet graft survival in an allogeneic murine model

JA Giraldo, RD Molano, HR Rengifo, C Fotino… - Acta biomaterialia, 2017 - Elsevier
Islet transplantation is a promising therapy for Type 1 diabetes mellitus; however, host
inflammatory and immune responses lead to islet dysfunction and destruction, despite …

Inhibition of Toll-like Receptor 4 Using Small Molecule, TAK-242, Protects Islets from Innate Immune Responses

J Mattke, CM Darden, S Vasu, MC Lawrence… - Cells, 2024 - mdpi.com
Islet transplantation is a therapeutic option to replace β-cell mass lost during type 1 or type
3c diabetes. Innate immune responses, particularly the instant blood-mediated inflammatory …

[HTML][HTML] Beyond Transduction: Anti-Inflammatory Effects of Cell Penetrating Peptides

J Lopuszynski, J Wang, M Zahid - Molecules, 2024 - mdpi.com
One of the bottlenecks to bringing new therapies to the clinic has been a lack of vectors for
delivering novel therapeutics in a targeted manner. Cell penetrating peptides (CPPs) have …

The role of interleukin-1β in destruction of transplanted islets

C Chen, P Rong, M Yang, X Ma, Z Feng… - Cell …, 2020 - journals.sagepub.com
Islet transplantation is a promising β-cell replacement therapy for type 1 diabetes, which can
reduce glucose lability and hypoglycemic episodes compared with standard insulin therapy …

Classes and applications of cell-penetrating peptides

Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
Classes and Applications of Cell-Penetrating Peptides | SpringerLink Skip to main content
Advertisement SpringerLink Account Menu Find a journal Publish with us Track your research …

[HTML][HTML] Chemical strategies for improving islet transplant outcomes

JM Quintana, AL Stinchcomb, JH Kostyo… - OBM …, 2018 - lidsen.com
Islet transplantation has proven to be a viable treatment for individuals suffering from both
Type 1 Diabetes Mellitus (T1D) and chronic pancreatitis. However, a variety of challenges …

[PDF][PDF] Beyond Transduction: Biological Effects of Cell Penetrating Peptides

J Lopuszynski, J Wang, M Zahid - 2024 - preprints.org
One of the bottlenecks to bringing new therapies to the clinic has been a lack of vectors for
delivering novel therapeutics in a targeted manner. Cell penetrating peptides (CPPs) have …