[HTML][HTML] Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment

AC Bibby, S Tsim, N Kanellakis, H Ball… - European …, 2016 - Eur Respiratory Soc
Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface,
predominantly caused by prior asbestos exposure. There is a global epidemic of malignant …

Malignant pleural mesothelioma

AS Tsao, I Wistuba, JA Roth, HL Kindler - Journal of clinical oncology, 2009 - ascopubs.org
Malignant pleural mesothelioma (MPM) is a deadly disease that occurs in 2,000 to 3,000
people each year in the United States. Although MPM is an extremely difficult disease to …

Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

NJ Vogelzang, JJ Rusthoven, J Symanowski… - Journal of clinical …, 2003 - ascopubs.org
Purpose: Patients with malignant pleural mesothelioma, a rapidly progressing malignancy
with a median survival time of 6 to 9 months, have previously responded poorly to …

[HTML][HTML] Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural …

DJ Sugarbaker, RM Flores, MT Jaklitsch… - The Journal of thoracic …, 1999 - Elsevier
Objectives: Our aim was to identify prognostic variables for long-term postoperative survival
in trimodality management of malignant pleural mesothelioma. Methods: From 1980 to 1997 …

[HTML][HTML] A phase II trial of surgical resection and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma

VW Rusch, K Rosenzweig, E Venkatraman… - The Journal of thoracic …, 2001 - Elsevier
Background: Surgical resection of malignant pleural mesothelioma is reported to have up to
an 80% rate of local recurrence. We performed a phase II trial of high-dose hemithoracic …

Phase II clinical trial of amatuximab, a chimeric antimesothelin antibody with pemetrexed and cisplatin in advanced unresectable pleural mesothelioma

R Hassan, HL Kindler, T Jahan, L Bazhenova… - Clinical cancer …, 2014 - AACR
Purpose: Amatuximab is a chimeric monoclonal antibody to mesothelin, a cell surface
glycoprotein highly expressed in malignant pleural mesothelioma (MPM). On the basis of its …

Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells

PC Schuberth, C Hagedorn, SM Jensen… - Journal of translational …, 2013 - Springer
Introduction Malignant pleural mesothelioma (MPM) is an incurable malignant disease,
which results from chronic exposition to asbestos in at least 70% of the cases. Fibroblast …

Important prognostic factors in patients with malignant pleural mesothelioma, managed surgically

VW Rusch, ES Venkatraman - The Annals of thoracic surgery, 1999 - Elsevier
Background. The factors influencing outcome after resection of malignant pleural
mesothelioma (MPM) are controversial. This analysis of a prospective surgical database …

[HTML][HTML] Malignant pleural mesothelioma: a population-based study of survival

MT Milano, H Zhang - Journal of Thoracic Oncology, 2010 - Elsevier
Introduction: This study characterizes the overall survival (OS) and variables affecting OS in
patients with malignant pleural mesothelioma. Methods: A total of 9701 patients with …

Malignant pleural mesothelioma

C Boutin, M Schlesser, C Frenay… - European Respiratory …, 1998 - Eur Respiratory Soc
The incidence of malignant pleural mesothelioma (MPM) has risen for some decades and is
expected to peak between 2010 and 2020. Up to now, no single treatment has been proven …