An overview of microRNAs: Biology, functions, therapeutics, and analysis methods

K Saliminejad, HR Khorram Khorshid… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in
posttranscriptional regulation of gene expression. They are powerful regulators of various …

Post-transcriptional control of miRNA biogenesis

G Michlewski, JF Cáceres - Rna, 2019 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …

Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications

YX Xu, SD Pu, X Li, ZW Yu, YT Zhang, XW Tong… - Pharmacological …, 2022 - Elsevier
Exosomes are discoid vesicles with a diameter of 40–160 nm. They are mainly derived from
the multivesicular body formed by the invagination of lysosomal particles in the cell, which …

Specific miRNA disease biomarkers in blood, serum and plasma: challenges and prospects

C Backes, E Meese, A Keller - Molecular diagnosis & therapy, 2016 - Springer
Significant effort has been devoted to discovering microRNA (miRNA) disease biomarkers.
In particular, miRNAs in whole blood or specific blood components are candidates for …

MicroRNA and transcription factor: key players in plant regulatory network

AFA Samad, M Sajad, N Nazaruddin, IA Fauzi… - Frontiers in plant …, 2017 - frontiersin.org
Recent achievements in plant microRNA (miRNA), a large class of small and non-coding
RNAs, are very exciting. A wide array of techniques involving forward genetic, molecular …

Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

MicroRNA biomarkers of Parkinson's disease in serum exosome-like microvesicles

XY Cao, JM Lu, ZQ Zhao, MC Li, T Lu, XS An… - Neuroscience letters, 2017 - Elsevier
Parkinson's disease (PD) is a progressive age-related debilitating motor disorder and the
second most common neurodegenerative disease after Alzheimer's disease. In this study …

Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

MicroRNAs in endometriosis: biological function and emerging biomarker candidates

S Bjorkman, HS Taylor - Biology of Reproduction, 2019 - academic.oup.com
MicroRNAs (miRNAs), a class of small noncoding RNA molecules, have been recognized as
key post-transcriptional regulators associated with a multitude of human diseases. Global …