Chronic obstructive pulmonary disease and asthma: mesenchymal stem cells and their extracellular vesicles as potential therapeutic tools

H Abbaszadeh, F Ghorbani… - Stem Cell Research & …, 2022 - Springer
Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and asthma,
are one of the most frequent causes of morbidity and mortality in the global. COPD is …

Translational potential of mesenchymal stem cells in regenerative therapies for human diseases: Challenges and opportunities

S Zhidu, T Ying, J Rui, Z Chao - Stem Cell Research & Therapy, 2024 - Springer
Advances in stem cell technology offer new possibilities for patients with untreated diseases
and disorders. Stem cell-based therapy, which includes multipotent mesenchymal stem cells …

Acute respiratory distress syndrome; a review of recent updates and a glance into the future

HF Ramji, M Hafiz, HH Altaq, ST Hussain, F Chaudry - Diagnostics, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory
failure that accounts for 10% of admissions to the ICU and is associated with approximately …

Apelin-13 attenuates lipopolysaccharide-induced inflammatory responses and acute lung injury by regulating PFKFB3-driven glycolysis induced by NOX4-dependent …

Y Yuan, W Wang, Y Zhang, Q Hong… - Journal of …, 2022 - Taylor & Francis
Purpose Acute lung injury (ALI) is a life-threatening condition with limited therapeutic
options. Macrophage inflammation plays a key role in the development of ALI. Abnormal …

Diabetic endothelial microangiopathy and pulmonary dysfunction

L Zhang, F Jiang, Y Xie, Y Mo, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a widespread metabolic condition with a high global
morbidity and mortality rate that affects the whole body. Their primary consequences are …

Unraveling the therapeutic effects of mesenchymal stem cells in asthma

F Mirershadi, M Ahmadi, A Rezabakhsh… - Stem Cell Research & …, 2020 - Springer
Asthma is a chronic inflammatory disease associated with airway hyper-responsiveness,
chronic inflammatory response, and excessive structural remodeling. The current …

Current therapeutic strategies for respiratory diseases using mesenchymal stem cells

M Wang, T Zhou, Z Zhang, H Liu, Z Zheng, H Xie - MedComm, 2021 - Wiley Online Library
Mesenchymal stromal/stem cells (MSCs) have a great potential to proliferate, undergo multi‐
directional differentiation, and exert immunoregulatory effects. There is already much …

Crocin attenuates inflammation of lung tissue in ovalbumin‐sensitized mice by altering the expression of endoplasmic reticulum stress markers

MR Aslani, M Amani, N Masrori, MH Boskabady… - Biofactors, 2022 - Wiley Online Library
Endoplasmic reticulum (ER) stress plays a pivotal role in the pathogenesis of asthma. The
present study aimed to investigate the reducing or suppressing effects of crocin in ovalbumin …

Application of exosomes for the alleviation of COVID‐19‐related pathologies

A Rezabakhsh, M Mahdipour… - Cell Biochemistry …, 2022 - Wiley Online Library
The pandemic of COVID‐19 caused worldwide concern. Due to the lack of appropriate
medications and the inefficiency of commercially available vaccines, lots of efforts are being …

Altered gene expression levels of IL-17/TRAF6/MAPK/USP25 axis and pro-inflammatory cytokine levels in lung tissue of obese ovalbumin-sensitized rats

MR Aslani, A Sharghi, MH Boskabady, H Ghobadi… - Life Sciences, 2022 - Elsevier
Aims The association between asthma and obesity has been shown but its accurate
mechanism is unknown. In the current study, we sought to investigate the gene expression …