[HTML][HTML] Effect of paraquat on cytotoxicity involved in oxidative stress and inflammatory reaction: A review of mechanisms and ecological implications

J Chen, Y Su, F Lin, M Iqbal, K Mehmood… - Ecotoxicology and …, 2021 - Elsevier
Paraquat (PQ) is a cheap and an effective herbicide, which is widely being used worldwide
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …

A comprehensive review of the therapeutic potential of curcumin nanoformulations

K Khezri, M Saeedi, H Mohammadamini… - Phytotherapy …, 2021 - Wiley Online Library
Today, due to the prevalence of various diseases such as the novel coronavirus (SARS‐
CoV‐2), diabetes, central nervous system diseases, cancer, cardiovascular disorders, and …

Sciadopitysin mitigates spermatological and testicular damage instigated by paraquat administration in male albino rats

MU Ijaz, M Qamer, A Hamza, H Ahmed, T Afsar… - Scientific reports, 2023 - nature.com
Paraquat (PQ) is a herbicide that has ability to induce testicular toxicity by producing reactive
oxygen species (ROS). Sciadopitysin (SPS) is a promising flavonoid that displays multiple …

Hepatorenal protective effect of nano-curcumin against nano‑copper oxide-mediated toxicity in rats: Behavioral performance, antioxidant, anti-inflammatory, apoptosis …

HG Tohamy, OS El Okle, AA Goma, MM Abdel-Daim… - Life Sciences, 2022 - Elsevier
Abstract Background Metal oxide nanoparticles (NPs) induce oxidative stress that can cause
cellular toxicity. A natural antioxidant that can be used to protect tissues from oxidative stress …

Nrf2-related therapeutic effects of curcumin in different disorders

S Ghafouri-Fard, H Shoorei, Z Bahroudi, BM Hussen… - Biomolecules, 2022 - mdpi.com
Curcumin is a natural polyphenol with antioxidant, antibacterial, anti-cancer, and anti-
inflammation effects. This substance has been shown to affect the activity of Nrf2 signaling, a …

The formulation of curcumin: 2-hydroxypropyl-β-cyclodextrin complex with smart hydrogel for prolonged release of curcumin

L Nikolić, M Urošević, V Nikolić, I Gajić, A Dinić… - Pharmaceutics, 2023 - mdpi.com
Curcumin comes from the plant species Curcuma longa and shows numerous
pharmacological activities. There are numerous curcumin formulations with gels or …

[HTML][HTML] An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat

C Nunes, P Singh, Z Mazidi, C Murphy, A Bourguignon… - Toxicology in Vitro, 2022 - Elsevier
Most OECD guidelines for chemical risk assessment include tests performed on animals,
raising financial, ethical and scientific concerns. Thus, the development of human-based …

[HTML][HTML] Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway

D Zhang, F Shen, S Ma, S Nan, Y Ma… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Paraquat (PQ), a highly effective and rapidly non-selective herbicide, mainly
targets the lungs and causes acute lung injury (ALI). So far, the scarcity of effective drug …

Liver injury in paraquat poisoning: A retrospective cohort study

Y Zhang, L Hou, D Yuan, J Wu, Y Wang, Y Yu… - Liver …, 2024 - Wiley Online Library
Abstract Background and Aims Liver injury is one of the common complications of paraquat
(PQ) poisoning, but whether the degree of liver injury is related to patient prognosis is still …

[HTML][HTML] Sulforaphane suppresses paraquat-induced oxidative damage in bovine in vitro-matured oocytes through Nrf2 transduction pathway

Z Feng, T Wang, Y Sun, S Chen, H Hao, W Du… - Ecotoxicology and …, 2023 - Elsevier
Sulforaphane (SFN), a bioactive phytocompound extracted from cruciferous plants, has
received increasing attention due to its vital cytoprotective role in eliminating oxidative free …