[HTML][HTML] A systematic review of in vitro and in vivo activities of anti-Toxoplasma drugs and compounds (2006–2016)

M Montazeri, M Sharif, S Sarvi, S Mehrzadi… - Frontiers in …, 2017 - frontiersin.org
The currently available anti-Toxoplasma agents have serious limitations. This systematic
review was performed to evaluate drugs and new compounds used for the treatment of …

Human toxoplasmosis–Searching for novel chemotherapeutics

M Antczak, K Dzitko, H Długońska - Biomedicine & Pharmacotherapy, 2016 - Elsevier
The protozoan Toxoplasma gondii, an obligate intracellular parasite, is an etiological agent
of human and animal toxoplasmosis. Treatment regimens for T. gondii-infected patients …

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

AL Burns, MG Dans, JM Balbin… - FEMS microbiology …, 2019 - academic.oup.com
Plasmodium spp. parasites that cause malaria disease remain a significant global-health
burden. With the spread of parasites resistant to artemisinin combination therapies in …

Anti-Toxoplasma activity of silver nanoparticles green synthesized with Phoenix dactylifera and Ziziphus spina-christi extracts which inhibits inflammation through …

RA Alajmi, WA Al-Megrin, D Metwally… - Bioscience …, 2019 - portlandpress.com
Toxoplasmosis constitutes a global infection caused by oblige intracellular apicomplexan
protozoan parasite Toxoplasma gondii. Although often asymptomatic, infection can result in …

Bloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei

E Rico, F Rojas, BM Mony, B Szoor… - Frontiers in cellular …, 2013 - frontiersin.org
African trypanosomes are sustained in the bloodstream of their mammalian hosts by their
extreme capacity for antigenic variation. However, for life cycle progression, trypanosomes …

Inorganic nanoparticles kill Toxoplasma gondii via changes in redox status and mitochondrial membrane potential

OS Adeyemi, Y Murata, T Sugi… - International journal of …, 2017 - Taylor & Francis
This study evaluated the anti-Toxoplasma gondii potential of gold, silver, and platinum
nanoparticles (NPs). Inorganic NPs (0.01–1,000 µg/mL) were screened for antiparasitic …

Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening

Y Deng, T Wu, SQ Zhai, CH Li - European journal of medicinal chemistry, 2019 - Elsevier
Toxoplasma gondii severely threaten the health of immunocompromised patients and
pregnant women as this parasite can cause several disease, including brain and eye …

How does Toxoplama gondii invade host cells?

K Kato - Journal of Veterinary Medical Science, 2018 - jstage.jst.go.jp
Toxoplasma gondii is a highly prevalent protozoon that can infect all warm-blooded animals,
including humans. It is frequently used as an Apicomplexan parasite model in research. In …

Imidazole derivatives as antiparasitic agents and use of molecular modeling to investigate the structure–activity relationship

OS Adeyemi, AO Eseola, W Plass, O Atolani, T Sugi… - Parasitology …, 2020 - Springer
Toxoplasmosis is a common parasitic disease caused by Toxoplasma gondii. Limitations of
available treatments motivate the search for better therapies for toxoplasmosis. In this study …

Metal nanoparticles restrict the growth of protozoan parasites

OS Adeyemi, NI Molefe, OJ Awakan… - Artificial cells …, 2018 - Taylor & Francis
Abstract The Trypanosoma and Toxoplasma spp, are etiological agents of diseases capable
of causing significant morbidity, mortality and economic burden, predominantly in …