RAGE and its ligands: molecular interplay between glycation, inflammation, and hallmarks of cancer—a review
G Palanissami, SFD Paul - Hormones and Cancer, 2018 - Springer
Risk of cancer especially of colon, breast, and pancreas is high in diabetic and obese
patients, with potential involvement of augmented expression of RAGE (receptor for …
patients, with potential involvement of augmented expression of RAGE (receptor for …
AGEs, RAGEs and s-RAGE; friend or foe for cancer
Impaired awareness of glycation biology in cancer initiation and progression is one of the
fundamental reasons for its meticulous investigation of the molecules involved in signalling …
fundamental reasons for its meticulous investigation of the molecules involved in signalling …
Food-derived 1, 2-dicarbonyl compounds and their role in diseases
M Hellwig, S Gensberger-Reigl, T Henle… - Seminars in cancer …, 2018 - Elsevier
Abstract Reactive 1, 2-dicarbonyl compounds (DCs) are generated from carbohydrates
during food processing and storage and under physiological conditions. In the recent …
during food processing and storage and under physiological conditions. In the recent …
Identification, formation, and occurrence of perlolyrine: A β-carboline alkaloid with a furan moiety in foods
T Herraiz, A Peña, A Salgado - Journal of Agricultural and Food …, 2023 - ACS Publications
β-Carbolines are naturally occurring bioactive alkaloids found in foods and in vivo. This
research reports the identification, characterization, mechanism of formation, and …
research reports the identification, characterization, mechanism of formation, and …
Do all roads lead to the Rome? The glycation perspective!
Oxidative, carbonyl, and glycative stress have gained substantial attention recently for their
alleged influence on cancer progression. Oxidative stress can trigger variable transcription …
alleged influence on cancer progression. Oxidative stress can trigger variable transcription …
Hypoxia driven glycation: Mechanisms and therapeutic opportunities
Tumor masses are deprived of oxygen and characterized by enhanced glucose uptake
followed by glycolysis. Elevated glucose levels induce non-enzymatic glycosylation or …
followed by glycolysis. Elevated glucose levels induce non-enzymatic glycosylation or …
Generation of autoantibodies against glycated fibrinogen: Role in diabetic nephropathy and retinopathy
The process of glycation, characterized by the non-enzymatic reaction between sugars and
free amino groups on biomolecules, is a key contributor to the development and progression …
free amino groups on biomolecules, is a key contributor to the development and progression …
[HTML][HTML] Hypoxia-induced degenerative protein modifications associated with aging and age-associated disorders
Aging is an inevitable time-dependent decline of various physiological functions that finally
leads to death. Progressive protein damage and aggregation have been proposed as the …
leads to death. Progressive protein damage and aggregation have been proposed as the …
An insight on the association of glycation with hepatocellular carcinoma
Hepato-cellular carcinoma (HCC) is one of the frequent cause of cancer-related death
worldwide and dominant form of primary liver cancer. However, the reason behind a steady …
worldwide and dominant form of primary liver cancer. However, the reason behind a steady …
Immunochemical studies on native and glycated LDL–An approach to uncover the structural perturbations
Glycation initiates with the non-enzymatic reaction of amino group of proteins and
lipoproteins by carbonyl group of sugar moiety and intermediates of glycative stress such as …
lipoproteins by carbonyl group of sugar moiety and intermediates of glycative stress such as …