Breast cancer is one of the main causes of premature death in women; current treatments have low selectivity, generating strong physical and psychological sequelae. The …
K Aguirre-Guataqui, M Márquez-Torres… - Antibiotics, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are considered to be a valuable source for the identification and/or design of promising candidates for the development of antifungal treatments, since …
Y Vargas-Casanova, CP Bravo-Chaucanés… - International Journal of …, 2024 - mdpi.com
Previous reports have demonstrated that the peptide derived from LfcinB, R-1-R, exhibits anti-Candida activity, which is enhanced when combined with an extract from the Bidens …
Anticancer peptides are increasingly being considered as alternative treatments for cancer due to their potency, selectivity, and low toxicity. Previously, the peptide LfcinB (21–25) Pal …
R Pasupuleti, S Riedl, L Saltor Núñez… - Protein …, 2023 - Wiley Online Library
Targeted killing of tumor cells while protecting healthy cells is the pressing priority in cancer treatment. Lectins that target a specific glycan marker abundant in cancer cells can be …
CFRC Guimarães, AS Félix, TAS Brandão… - Amino Acids, 2023 - Springer
Peptides are remarkably interesting alternatives to several applications. In particular, antimicrobial sequences have raised major interest of the scientific community due to the …
AG López-Sánchez, KG Rodríguez-Mejía… - Processes, 2024 - mdpi.com
Synthetic peptides are commonly obtained by means of solid-phase peptide synthesis (SPPS), in which separation of the peptide from the solid support requires treatment with …
Matrix effect and sample pretreatment significantly affect the percentage recovery of peptides in biological matrices, affecting the method robustness and accuracy. To counteract …
DS Insuasty-Cepeda… - Royal Society …, 2023 - royalsocietypublishing.org
The dimeric peptide 26 [F]:(RRWQWR F KKLG) 2-K-Ahx has exhibited a potent cytotoxic effect against breast cancer cell lines, with position 26 (F) being the most relevant for anti …