Focusing on the recent literature (since 2000), this review outlines the main synthetic
approaches for the preparation of 5′-mono-, 5′-di-, and 5′-triphosphorylated …

Industrial and laboratory methods for incorporating phosphorus atoms into molecules within
the framework of Green Chemistry are in their infancy. Current practice requires large inputs …

Pentametaphosphate is the little studied cyclic pentamer of the metaphosphate ion,[PO3] 55–
. We show that the doubly protonated form of this pentamer can be selectively dehydrated to …

Phosphoramidite analogues of modified cyclotriphosphates provide a general and step-
economical synthesis of nucleoside triphosphates and analogues on scale without the need …

Commercial phosphorus pentoxide reacts with some N-donor bases to give the adducts
P2O5L2 and P4O10L3 (L= DABCO, pyridine, 4-tert-butylpyridine). The DABCO adducts …

Phosphorylation under plausible prebiotic conditions continues to be one of the defining
issues for the role of phosphorus in the origins of life processes. In this review, we cover the …

While nucleoside 5′-triphosphates are precursors for RNA in modern biology, the
presumed difficulty of making these triphosphates on Hadean Earth has caused many …

Oligophosphates play essential roles in biochemistry, and considerable research has been
directed toward the synthesis of both naturally occurring oligophosphates and their synthetic …

Life's origins have always been a scientific puzzle. Understanding the production of
biomolecules is crucial for understanding the evolution of life on Earth. Numerous studies on …

Trimetaphosphate (TriMP,[P3O9] 3–) reacts with PyAOP ([(H8C4N) 3PON4C5H3][PF6]) to
yield an activated TriMP,[P3O9P (NC4H8) 3]−(1), incorporating a phosphonium moiety …