Red blood cell (RBC) transfusion is common in critically ill, postsurgical, and posttrauma
patients in whom both systemic inflammation and immune suppression are associated with …

Red blood cells (RBCs) units are the most requested transfusion product worldwide.
Indications for transfusion include symptomatic anaemia, acute sickle cell crisis, and acute …

BACKGROUND. Some countries have limited the maximum allowable storage duration for
red cells to 5 weeks before transfusion. In the US, red blood cells can be stored for up to 6 …

Importance Increasing evidence supports the role of red blood cells (RBCs) in physiological
hemostasis and pathologic thrombosis. Red blood cells are commonly transfused in the …

Transfusion‐related immunomodulation (TRIM) in the intensive care unit (ICU) is difficult to
define and likely represents a complicated set of physiologic responses to transfusion …

Transfusion reactions are common occurrences, and clinicians who order or transfuse blood
components need to be able to recognize adverse sequelae of transfusion. The differential …

The multiple roles of iron in the body have been known for decades, particularly its
involvement in iron overload diseases such as hemochromatosis. More recently, compelling …

Many research institutions, clinical diagnostic laboratories, and blood banks are desperately
searching for a possibility to identify and quantify heme in different physiological and …

Red blood cell storage lesion (RSL) is a multifaceted biological phenomenon. It refers to
deterioration in RBC quality that is characterized by lethal and sub-lethal, reversible and …

BACKGROUND Pathogen reduction treatment using riboflavin and ultraviolet light
illumination (Mirasol) effectively reduces the risk of transfusion‐transmitted infections. This …