[HTML][HTML] The Physiological Functions and Therapeutic Potential of Hypoxia-Inducible Factor-1α in Vascular Calcification
Z Zhang, D Wang, R Xu, X Li, Z Wang… - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
HIF-1α plays a crucial regulatory role in vascular calcification (VC), primarily influencing the
osteogenic differentiation of VSMCs through oxygen-sensing mechanisms. Under hypoxic …
osteogenic differentiation of VSMCs through oxygen-sensing mechanisms. Under hypoxic …
[HTML][HTML] Metabolic Side Effects from Antipsychotic Treatment with Clozapine Linked to Aryl Hydrocarbon Receptor (AhR) Activation
K Fehsel - Biomedicines, 2024 - mdpi.com
Metabolic syndrome (MetS) is the most common adverse drug reaction from psychiatric
pharmacotherapy. Neuroreceptor blockade by the antipsychotic drug clozapine induces …
pharmacotherapy. Neuroreceptor blockade by the antipsychotic drug clozapine induces …
Suppressing IGF2R mitigates hypoxia-induced apoptosis by reducing the expression of pro-apoptotic factor BAX
X Guo, X Fan, C Xie, AE Afe, Y Yang, R Zhou - International Journal of …, 2025 - Elsevier
Oxidative stress caused by hypoxia can lead to serious bodily damage and functional
degradation. Our previous study in pigs showed that the insulin-like growth factor II receptor …
degradation. Our previous study in pigs showed that the insulin-like growth factor II receptor …
Investigating the regulatory mechanism of glucose metabolism by ubiquitin-like protein MNSFβ
M Kono, K Yamasaki, M Nakamura - Molecular Biology Reports, 2024 - Springer
Background Monoclonal nonspecific suppressor factor β (MNSFβ), a ubiquitously expressed
member of the ubiquitin-like protein family, is associated with diverse cell regulatory …
member of the ubiquitin-like protein family, is associated with diverse cell regulatory …