Background Cholangiocarcinomas are a heterogeneous group of malignancies arising from
a number of cells of origin along the biliary tree. Although most cases in Western countries …

Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …

Cholangiocarcinoma (CCA) is an epithelial can-cer originating from the bile ducts with
features of cholangiocyte differentiation. 1 CCA is the second most common primary hepatic …

The introduction of selective COX-2 inhibitors (so-called 'coxibs') has demonstrated
tremendous commercial success due to their claimed lower potential of serious …

Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of
biliary tract differentiation. CCA is the second most common primary liver tumour and the …

Nonsteroidal antiinflammatory drugs (NSAIDs) appear to reduce the risk of developing
cancer. One mechanism through which NSAIDs act to reduce carcinogenesis is to inhibit the …

Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with very poor
prognosis. Genome-wide, high-throughput technologies have made major advances in …

Simple Summary An increasing number of cancer cases has been reported throughout the
years. Most cancers are linked to unhealthy lifestyles and genetic inheritance. Nevertheless …

Background Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) with anti-
inflammatory, analgestic, and antipyretic properties. It is approved for the treatment of …

Cholangiocarcinomas are devastating cancers that are increasing in both their worldwide
incidence and mortality rates. The challenges posed by these often lethal biliary tract …