Triple negative breast cancer (TNBC), which is typically lack of expression of estrogen
receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 …

Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Focal adhesion kinase (FAK), a nonreceptor cytoplasmic tyrosine kinase, is a vital
participant in primary cellular functions, such as proliferation, survival, migration, and …

Triple-negative breast cancer (TNBC) is a particularly aggressive and heterogeneous
disease with few effective targeted therapies and precision therapeutic options over a long …

The G protein-coupled estrogen receptor (GPER) is a seven-transmembrane-domain
receptor that mediates non-genomic estrogen related signaling. After ligand activation …

Background Understanding the intricate signaling network involved in triple-negative breast
cancer (TNBC) represents a challenge for developing novel therapeutic approaches. Here …

Background Hypoxia plays a relevant role in tumor-related inflammation toward the
metastatic spread and cancer aggressiveness. The pro-inflammatory cytokine interleukin-1β …

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase and an adaptor protein that
primarily regulates adhesion signaling and cell migration. FAK promotes cell survival in …

Background and objective Historically, amygdalin has been used as alternative medicine or
in vitro and in vivo studies, but no single study exists which discusses the structural …

Triple-negative breast cancer (TNBC) is an aggressive breast tumor subtype that currently
lacks targeted treatment options. The role played by the insulin-like growth factor-1 (IGF-1) …