Revisiting excitotoxicity in traumatic brain injury: from bench to bedside

D Baracaldo-Santamaría, DF Ariza-Salamanca… - Pharmaceutics, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …

Animal models of traumatic brain injury: a review of pathophysiology to biomarkers and treatments

A Petersen, M Soderstrom, B Saha… - Experimental brain …, 2021 - Springer
Traumatic brain injury (TBI) is one of the main causes of death and disability in both civilian
and military population. TBI may occur via a variety of etiologies, all of which involve trauma …

Nutritional considerations and strategies to facilitate injury recovery and rehabilitation

AE Smith-Ryan, KR Hirsch, HE Saylor… - Journal of athletic …, 2020 - meridian.allenpress.com
Nutritional interventions are not commonly a standard of care in rehabilitation interventions.
A nutritional approach has the potential to be a low-cost, high-volume strategy that …

A review of traumatic brain injury and the gut microbiome: insights into novel mechanisms of secondary brain injury and promising targets for neuroprotection

CS Zhu, R Grandhi, TT Patterson, SE Nicholson - Brain sciences, 2018 - mdpi.com
The gut microbiome and its role in health and disease have recently been major focus areas
of research. In this review, we summarize the different ways in which the gut microbiome …

[HTML][HTML] Mitigating traumatic brain injury: a narrative review of supplementation and dietary protocols

F Conti, JJ McCue, P DiTuro, AJ Galpin, TR Wood - Nutrients, 2024 - mdpi.com
Traumatic brain injuries (TBIs) constitute a significant public health issue and a major source
of disability and death in the United States and worldwide. TBIs are strongly associated with …

Human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in TBI models through rescuing neuronal …

C Bamshad, MH Roudkenar, M Abedinzade… - International …, 2023 - Elsevier
Each year, traumatic brain injury (TBI) causes a high rate of mortality throughout the world
and those who survive have lasting disabilities. Given that the brain is a particularly dynamic …

Mesenchymal stem cell-induced anti-neuroinflammation against traumatic brain injury

B Cozene, N Sadanandan, J Farooq… - Cell …, 2021 - journals.sagepub.com
Traumatic brain injury (TBI) is a pervasive and damaging form of acquired brain injury (ABI).
Acute, subacute, and chronic cell death processes, as a result of TBI, contribute to the …

Effects of curcuminoids on inflammatory and oxidative stress biomarkers and clinical outcomes in critically ill patients: A randomized double‐blind placebo‐controlled …

H Zahedi, MJ Hosseinzadeh‐Attar… - Phytotherapy …, 2021 - Wiley Online Library
Experimental studies have suggested the beneficial effects of curcuminoids as natural
polyphenols against traumatic brain injury (TBI). The aim of this study was to investigate the …

Omega-3 fatty acids and vitamin D decrease plasma T-tau, GFAP, and UCH-L1 in experimental traumatic brain injury

AG Scrimgeour, ML Condlin, A Loban… - Frontiers in Nutrition, 2021 - frontiersin.org
Traumatic brain injury (TBI) results in neuronal, axonal and glial damage. Interventions
targeting neuroinflammation to enhance recovery from TBI are needed. Exercise is known to …

Blood biomarkers for assessment of mild traumatic brain injury and chronic traumatic encephalopathy

MI Hiskens, AG Schneiders, M Angoa-Pérez… - Biomarkers, 2020 - Taylor & Francis
Mild traumatic brain injuries (mTBI) are prevalent and can result in significant debilitation.
Current diagnostic methods have implicit limitations, with clinical assessment tools reliant on …