Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches

TB Emran, A Shahriar, AR Mahmud, T Rahman… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …

Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance

N Erin, J Grahovac, A Brozovic, T Efferth - Drug Resistance Updates, 2020 - Elsevier
It is well established that multifactorial drug resistance hinders successful cancer treatment.
Tumor cell interactions with the tumor microenvironment (TME) are crucial in epithelial …

Taxanes in cancer treatment: Activity, chemoresistance and its overcoming

L Mosca, A Ilari, F Fazi, YG Assaraf, G Colotti - Drug Resistance Updates, 2021 - Elsevier
Since 1984, when paclitaxel was approved by the FDA for the treatment of advanced
ovarian carcinoma, taxanes have been widely used as microtubule-targeting antitumor …

exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids

H Lai, Y Li, H Zhang, J Hu, J Liao, Y Su… - Nucleic acids …, 2022 - academic.oup.com
Extracellular vesicles (EVs) are small membranous vesicles that contain an abundant cargo
of different RNA species with specialized functions and clinical implications. Here, we …

New insights into antiangiogenic therapy resistance in cancer: Mechanisms and therapeutic aspects

M Huang, Y Lin, C Wang, L Deng, M Chen… - Drug resistance …, 2022 - Elsevier
Angiogenesis is a hallmark of cancer and is required for tumor growth and progression.
Antiangiogenic therapy has been revolutionarily developing and was approved for the …

Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

Mechanisms of resistance and current treatment options for glioblastoma multiforme (GBM)

SSK Yalamarty, N Filipczak, X Li, MA Subhan… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …

Extracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion

W Tian, N Lei, J Zhou, M Chen, R Guo, B Qin, Y Li… - Cell Death & …, 2022 - nature.com
Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …