Current trends in the characterization and monitoring of vascular response to cancer therapy
Tumor vascular physiology is an important determinant of disease progression as well as
the therapeutic outcome of cancer treatment. Angiogenesis or the lack of it provides crucial …
the therapeutic outcome of cancer treatment. Angiogenesis or the lack of it provides crucial …
Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging
Abstract The Enhanced Permeability and Retention (EPR) effect is extensively used in drug
delivery research. Taking into account that EPR is a highly variable phenomenon, we have …
delivery research. Taking into account that EPR is a highly variable phenomenon, we have …
Preclinical molecular imaging for precision medicine in breast cancer mouse models
MF Fiordelisi, L Auletta, L Meomartino… - Contrast media & …, 2019 - Wiley Online Library
Precision and personalized medicine is gaining importance in modern clinical medicine, as
it aims to improve diagnostic precision and to reduce consequent therapeutic failures. In this …
it aims to improve diagnostic precision and to reduce consequent therapeutic failures. In this …
Non-invasive imaging for studying anti-angiogenic therapy effects
Noninvasive imaging plays an emerging role in preclinical and clinical cancer research and
has high potential to improve clinical translation of new drugs. This article summarises and …
has high potential to improve clinical translation of new drugs. This article summarises and …
Radiomic analysis of contrast-enhanced ultrasound data
Radiomics describes the use radiological data in a quantitative manner to establish
correlations in between imaging biomarkers and clinical outcomes to improve disease …
correlations in between imaging biomarkers and clinical outcomes to improve disease …
[HTML][HTML] Erythropoietin improves the accumulation and therapeutic effects of carboplatin by enhancing tumor vascularization and perfusion
Recombinant human erythropoietin (rhuEpo) is currently under debate for the treatment of
chemotherapy-induced anemia due to clinical trials showing adverse effects in Epo-treated …
chemotherapy-induced anemia due to clinical trials showing adverse effects in Epo-treated …
Failure of annexin-based apoptosis imaging in the assessment of antiangiogenic therapy effects
Background Molecular apoptosis imaging is frequently discussed to be useful for monitoring
cancer therapy. We demonstrate that the sole assessment of therapy effects by apoptosis …
cancer therapy. We demonstrate that the sole assessment of therapy effects by apoptosis …
Low-dose molecular ultrasound imaging with E-selectin-targeted PBCA microbubbles
Purpose Our objective was to determine the lowest diagnostically effective dose for E-
selectin-targeted poly n-butyl cyanoacrylate (PBCA)-shelled microbubbles and to apply it to …
selectin-targeted poly n-butyl cyanoacrylate (PBCA)-shelled microbubbles and to apply it to …
Rhodamine-loaded intercellular adhesion molecule–1-targeted microbubbles for dual-modality imaging under controlled shear stresses
Background—The ability to image incipient atherosclerosis is based on the early events
taking place at the endothelial level. We hypothesized that the expression of intercellular …
taking place at the endothelial level. We hypothesized that the expression of intercellular …
Characterizing breast masses using an integrative framework of machine learning and CEUS-based radiomics
BA Varghese, S Lee, S Cen, A Talebi, P Mohd… - Journal of …, 2022 - Springer
Aims We evaluated the performance of contrast-enhanced ultrasound (CEUS) based on
radiomics analysis to distinguish benign from malignant breast masses. Methods 131 …
radiomics analysis to distinguish benign from malignant breast masses. Methods 131 …