Recent advances in integrated solid-state nanopore sensors

M Rahman, MJN Sampad, A Hawkins, H Schmidt - Lab on a Chip, 2021 - pubs.rsc.org
The advent of single-molecule probing techniques has revolutionized the biomedical and
life science fields and has spurred the development of a new class of labs-on-chip based on …

Field effect nanofluidics

S Prakash, AT Conlisk - Lab on a Chip, 2016 - pubs.rsc.org
Nanoscale fluid transport through conduits in the 1–100 nm range is termed as nanofluidics.
Over the past decade or so, significant scientific and technological advances have occurred …

On-demand intracellular delivery of single particles in single cells by 3D hollow nanoelectrodes

JA Huang, V Caprettini, Y Zhao, G Melle… - Nano …, 2019 - ACS Publications
Delivery of molecules into intracellular compartments is one of the fundamental
requirements in molecular biology. However, the possibility of delivering a precise number …

Single molecule delivery into living cells

CC Chau, CM Maffeo, A Aksimentiev… - Nature …, 2024 - nature.com
Controlled manipulation of cultured cells by delivery of exogenous macromolecules is a
cornerstone of experimental biology. Here we describe a platform that uses nanopipettes to …

Methods for protein delivery into cells: from current approaches to future perspectives

C Chau, P Actis, E Hewitt - Biochemical Society Transactions, 2020 - portlandpress.com
The manipulation of cultured mammalian cells by the delivery of exogenous
macromolecules is one of the cornerstones of experimental cell biology. Although the …

Selective multidetection using nanopores

M Taniguchi - Analytical chemistry, 2015 - ACS Publications
Recent developments in nanopore devices are re-examined from the perspective of their
selectivity for detecting single or multiple analytes. Although nanopore devices have been …

Controllable shrinking of glass capillary nanopores down to sub-10 nm by wet-chemical silanization for signal-enhanced DNA translocation

X Xu, C Li, Y Zhou, Y Jin - ACS sensors, 2017 - ACS Publications
Diameter is a major concern for nanopore based sensing. However, directly pulling glass
capillary nanopore with diameter down to sub-10 nm is very difficult. So, post treatment is …

Detecting Single Molecule Deoxyribonucleic Acid in a Cell Using a Three‐Dimensionally Integrated Nanopore

M Tsutsui, K Yokota, A Arima, T Washio, Y Baba… - Small …, 2021 - Wiley Online Library
Amplification‐free genome analysis can revolutionize biology and medicine by uncovering
genetic variations among individuals. Here, the authors report on a 3D‐integrated nanopore …

Think small: nanopores for sensing and synthesis

W Timp, AM Nice, EM Nelson, V Kurz… - IEEE …, 2014 - ieeexplore.ieee.org
It is now possible to manipulate individual molecules using a nanopore to read DNA and
proteins, or write DNA by inserting mini-genes into cells. Furthermore, development of these …

Recent advances of nanopore technique in single cell analysis

X Zhang, Z Su, Y Zhao, D Wu, Y Wu, G Li - Analyst, 2024 - pubs.rsc.org
Single cells and their dynamic behavior are closely related to biological research.
Monitoring their dynamic behavior is of great significance for disease prevention. How to …