Alginate is a biopolymer extensively utilized in numerous applications. Hydrogel forming
property, chemical structure with hydroxyl and carboxylate moieties, biocompatibility …

Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …

The objective of the study was to develop chitosan (CH) coated sodium alginate–chitosan
(SA–CH) nanoparticles, ie CH-SA–CH NPs loaded with 5-FU for ophthalmic delivery. Drug …

Introduction: In situ gel systems refer to a class of novel delivery vehicles, composed of
natural, semisynthetic or synthetic polymers, which present the unique property of sol–gel …

Nowadays chitosan nanoparticles (CS NPs) have been extensively considered for
biomedical applications. The purpose of this paper is to summarize the results of larvicidal …

Nanoscale drug delivery systems (NDDS) have shown great potential in tumor treatment
due to its unique advantages, especially its unique enhanced permeability and retention …

The most important risk associated with glaucoma is the onset and progression of
intraocular pressure. The objective of this study was to formulate in situ gel of chitosan …

The unique properties and characteristics of ocular tissues and the whole set of defence
mechanisms of the ocular globe make the instillation of ocular drugs into a difficult task with …

For decades, studies on drug-release kinetics have been an important topic in the field of
drug delivery because they provide important insights into the mechanism of drug release …

Context: Conventional ophthalmic solutions often eliminate rapidly after administration and
cannot provide and maintain an adequate concentration of drug in the pre-corneal area …