Cancer is a leading cause of death worldwide, and its incidence is rising with numbers
expected to increase 70% in the next two decades. The fact that current mainline treatments …

Abstract Background The aquaporins (AQPs) are a family of 13 small hydrophobic integral
transmembrane water channel proteins involved in transcellular and transepithelial water …

Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide, and it
is the second leading cause of cancer-related mortality. Aquaporin 9 (AQP9) is an essential …

Background Glioblastomas are invasive therapy resistant brain tumors with extremely poor
prognosis. The Glioma initiating cell (GIC) population contributes to therapeutic resistance …

Brain primary tumors are among the most diverse and complex human cancers, and they
are normally classified on the basis of the cell-type and/or the grade of malignancy (the most …

Aquaporins (AQPs) are membrane proteins allowing permeation of water, glycerol &
hydrogen peroxide across biomembranes, and playing an important role in water …

Extracellular vesicles are involved in a great variety of physiological events occurring in the
nervous system, such as cross talk among neurons and glial cells in synapse development …

Aquaporins (AQPs) are a family of membrane water channel proteins that control osmotically-
driven water transport across cell membranes. Recent studies have focused on the …

Herpes simplex encephalitis (HSE), targeting the limbic system, is the most common cause
of viral encephalitis in the Western world. Two pathways for viral entry to the central nervous …

Aquaporins (AQPs) mediate water flux between the four distinct water compartments in the
central nervous system (CNS). In the present chapter, we mainly focus on the expression …