The coordinated regulation between cellular glucose uptake and endogenous glucose
production is indispensable for the maintenance of constant blood glucose concentrations …

Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis,
resulting in hyperglycaemia. Although current diabetes treatments have exhibited some …

Tissue environment plays a powerful role in establishing and maintaining the distinct
phenotypes of resident macrophages, but the underlying molecular mechanisms remain …

Reversible acetylation was initially described as an epigenetic mechanism regulating DNA
accessibility. Since then, this process has emerged as a controller of histone and nonhistone …

Salt-inducible kinases (SIKs) belong to AMP-activated protein kinase (AMPK) family, and
functions mainly involve in regulating energy response-related physiological processes …

Mammals undergo regular cycles of fasting and feeding that engage dynamic transcriptional
responses in metabolic tissues. Here we review advances in our understanding of the gene …

Osteoclasts are the exclusive bone-resorbing cells, playing a central role in bone
metabolism, as well as the bone damage that occurs under pathological conditions,. In …

Background and Purpose Recent reports have suggested that salidroside could protect
cardiomyocytes from oxidative injury and stimulate glucose uptake in skeletal muscle cells …

The formation of the embryonic brain and spinal cord begins as the neural plate bends to
form the neural folds, which meet and adhere to close the neural tube. The neural ectoderm …

Production of amphiregulin (Areg) by regulatory T (Treg) cells promotes repair after acute
tissue injury. Here, we examined the function of Treg cells in non-alcoholic steatohepatitis …