The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …

The onco-suppressor p53 is a transcription factor that regulates a wide spectrum of genes
involved in various cellular functions including apoptosis, cell cycle arrest, senescence …

Hedgehog (Hh) signalling regulates hepatic fibrogenesis. MicroRNAs (miRNAs) mediate
various cellular processes; however, their role in liver fibrosis is unclear. Here we investigate …

The NF-κB pathway, a critical regulator of apoptosis, plays a key role in many normal cellular
functions. Genetic alterations and other mechanisms leading to constitutive activation of the …

In recent years, miR-124 has emerged as a critical modulator of immunity and inflammation.
Here, we summarize studies on the function and mechanism of miR-124 in the immune …

Parkinson's disease (PD) is a neurological degenerative disorder that is partially induced by
inflammation in the neural system. To explore the roles of disordered microRNAs in the …

Acute lymphoblastic leukemia (ALL) is characterized by the accumulation of abnormal
lymphoblasts in the bone marrow and blood. Though great progress has been made for …

Aging is a multifactorial process characterized by the progressive deterioration of
physiological functions. Among the multiple molecular mechanisms, microRNAs (miRNAs) …

Atopic dermatitis (AD) is a chronic and recurrent inflammatory skin disease, affecting up to
10% to 20% of children and 3% of adults. Although allergen sensitization, skin barrier …

p53 is known as the guardian of the genome and plays various roles in DNA damage and
cancer suppression. The p53 gene was found to express multiple p53 splice variants …