According to the WHO, cancer is the second leading cause of death in the world. This is an
important global problem and a major challenge for researchers who have been trying to …

Adamantane is a weakly functional hydrocarbon widely used to develop new drug
molecules to improve their pharmacokinetic and pharmacodynamic parameters. The …

Muramyl dipeptide (MDP) is the smallest essential peptidoglycan substructure capable of
promoting both innate and adaptive immune responses. Herein, we report on the design …

C-Glycosyl compounds (C-glycosides) are a class of saccharide derivatives with improved
stability over their O-linked counterparts. This paper reports the synthesis of several trans-2 …

Cu (I)-catalyzed azide− alkyne 1, 3-dipolar cycloaddition (CuAAC)-commonly known as the
“click reaction”-serves as the most effective and highly reliable tool for facile construction of …

Incorporation of a trifluoromethyl group with 1, 2, 3-triazoles motifs was described. We
explored a click reaction approach for regioselective synthesis of 1-susbstituted-4 …

Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine, MDP) is the smallest
peptidoglycan fragment able to trigger an immune response by activating the NOD2 …

Sažetak U sklopu ovog diplomskog rada razvijen je sintetski put priprave tripeptidnih
derivata ferocena, potencijalnih NOD2 agonista. Ciljni spojevi 6, 8 i 9 sintetizirani su …

Sažetak U sklopu diplomskog rada opisana je priprava triju ferocenskih estera
manoziliranog desmuramil-dipeptida, L-Ala-D-isoGln. Konvergentnim pristupom sintezi …