Environmental and ecotoxicological effects of drugs used for the treatment of COVID 19

D Efrain Merma Chacca, I Maldonado… - … in Environmental Science, 2022 - frontiersin.org
Consumption of different pharmaceuticals has increased since the COVID-19 pandemic.
Some health institutions worldwide approved the use of drugs such as ivermectin …

Hydroxychloroquine and cardiotoxicity

S Dey, K Lee, S Subhan, JY Ash… - Cardiology in …, 2023 - journals.lww.com
Hydroxychloroquine (HCQ) has been used for rheumatological diseases such as systemic
lupus erythematous and rheumatoid arthritis and demonstrated to improve clinical symptoms …

[PDF][PDF] Controlled release studies of hydroxychloroquine sulphate (hcq) drug-using biodegradable polymeric sodium alginate and lignosulphonic acid blends

SG Reddy - Rasayan J. Chem, 2021 - rasayanjournal.co.in
ABSTRACT HCQ an antimalarial drug is one of the most in-demand medications globally
since COVID-19 pandemics. To study the controlled release of HCQ in physiological …

Whole blood hydroxychloroquine: Does genetic polymorphism of cytochrome P450 enzymes have a role?

N Jatta, J Stanslas, ACH Yong, WC Ho… - Clinical and …, 2023 - Springer
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of
clinical manifestations and multifactorial etiologies ranging from environmental to genetic …

Evaluation of controlled hydroxychloroquine releasing performance from calcium-alginate beads

C Armutcu, S Pişkin - Hittite Journal of Science and Engineering, 2021 - dergipark.org.tr
The aim of this study was to develop an effective controlled drug delivery system based on
alginate beads for the treatment of autoimmune diseases such as Rheumatoid Arthritis (RA) …

The In Vitro, In Vivo, and PBPK Evaluation of a Novel Lung-Targeted Cardiac-Safe Hydroxychloroquine Inhalation Aerogel

MM Alsmadi, MM Jaradat, RM Obaidat, M Alnaief… - AAPS …, 2023 - Springer
Hydroxychloroquine (HCQ) was repurposed for COVID-19 treatment. Subtherapeutic HCQ
lung levels and cardiac toxicity of oral HCQ were overcome by intratracheal (IT) …

A Comprehensive Assessment of Environmental Implications, Ecotoxicity and Bioaccumulation Potential of Repurposed Drug Hydroxychloroquine: From Challenges …

P Gupta, V Rani - Reviews of Environmental Contamination and …, 2024 - Springer
An unprecedented rise in the demand for the drug hydroxychloroquine (HCQ) worldwide
and its utilisation has resulted in its upscale manufacturing. Being ecologically persistent …

A high sensitivity adsorptive-electrochemical method for rapid and portable determination of hydroxychloroquine

JPC Silva, DR Santos-Neto, CEC Lopes… - Journal of Solid State …, 2024 - Springer
Abstract On March 11, 2020, the World Health Organization declared the coronavirus
disease pandemic, caused by the SARS-CoV-2 virus. This declaration propelled the drug …

Central composite rotatable design for non-convex optimization of removal efficiency of hydroxychloroquine in an electrochemical cell

A Regalado-Méndez, D Vásquez-Hernández… - Journal of Solid State …, 2024 - Springer
Hydroxychloroquine sulfate (HCQ), an against-COVID-19 drug, is a dangerous organic
compound in wastewater. In this study, 0.6 L of an HCQ solution (50 mg L− 1) was electro …

[HTML][HTML] Hydroxychloroquine Mitigates Cytokine Storm and Prevents Critical Illness Neuromyopathy in a Rat Sepsis Model

E Eygi, O Kucuk, S Aydemir, M Atilgan, R Dokuyucu… - Medicina, 2024 - mdpi.com
Background and Objectives: It is known that critical illness and associated neuromuscular
problems begin to appear in patients hospitalized in the intensive care unit (ICU) for more …