[HTML][HTML] Empowering biomedical discovery with AI agents

S Gao, A Fang, Y Huang, V Giunchiglia, A Noori… - Cell, 2024 - cell.com
We envision" AI scientists" as systems capable of skeptical learning and reasoning that
empower biomedical research through collaborative agents that integrate AI models and …

Exposing the causal effect of C-reactive protein on the risk of type 2 diabetes mellitus: a Mendelian randomization study

L Cheng, H Zhuang, S Yang, H Jiang, S Wang… - Frontiers in …, 2018 - frontiersin.org
As a biomarker of inflammation, C-reactive protein (CRP) has attracted much attention due
to its role in the incidence of type 2 diabetes mellitus (T2DM). Prospective studies have …

The bidirectional causal relationships of insomnia with five major psychiatric disorders: a Mendelian randomization study

X Gao, LX Meng, KL Ma, J Liang, H Wang… - European …, 2019 - cambridge.org
Background: Several observational studies have investigated the association of insomnia
with psychiatric disorders. Such studies yielded mixed results, and whether these …

Casual associations between brain structure and sarcopenia: A large‐scale genetic correlation and mendelian randomization study

G Yang, W Xie, B Li, G Zhao, J Li, W Xiao, Y Li - Aging Cell, 2024 - Wiley Online Library
Sarcopenia presenting a critical challenge in population‐aging healthcare. The elucidation
of the interplay between brain structure and sarcopenia necessitates further research. The …

Interactions between meat intake and genetic variation in relation to colorectal cancer

V Andersen, U Vogel - Genes & nutrition, 2015 - Springer
Meat intake is associated with the risk of colorectal cancer. The objective of this systematic
review was to evaluate interactions between meat intake and genetic variation in order to …

Clinical relevance of point mutations in the 23S rRNA gene in Helicobacter pylori eradication: a prospective, observational study

CG Park, S Kim, EJ Lee, HS Jeon, S Han - Medicine, 2018 - journals.lww.com
Clarithromycin-based triple therapy is prescribed worldwide for Helicobacter pylori
eradication. However, increases in the clarithromycin resistance of H pylori are thought to be …

Admixture mapping of genetic variants for uterine fibroids

K Zhang, H Wiener, B Aissani - Journal of human genetics, 2015 - nature.com
Uterine leiomyoma (UL) are benign neoplasms arising from the smooth muscle cells of the
uterus. One of the established risk factors for UL is African American ethnicity. Studies have …

Bidirectional relationship between 56 peripheral inflammatory regulators and sleep apnea syndrome: A Mendelian randomization study

Y Sun, F Wang, S Li - Heart & Lung, 2023 - Elsevier
Background Peripheral inflammation plays an potential role in both pathogenesis and
outcomes of sleep apnea syndrome (SAS). However, this topic has not been explored at the …

Multiple hits for the association of uterine fibroids on human chromosome 1q43

B Aissani, H Wiener, K Zhang - PloS one, 2013 - journals.plos.org
Uterine leiomyomas (or fibroids) are the most common tumors in women of reproductive
age. Early studies of two familial cancer syndromes, the multiple cutaneous and uterine …

[HTML][HTML] Genetic determinants of uterine fibroid size in the multiethnic NIEHS uterine fibroid study

B Aissani, K Zhang, H Wiener - International journal of molecular …, 2015 - ncbi.nlm.nih.gov
We conducted a follow-up association study across extended candidate chromosomal
regions for uterine leiomyoma (UL), or fibroids, to search for loci influencing the size of UL in …