Cannabis pharmacogenomics: a path to personalized medicine

M Babayeva, ZG Loewy - Current Issues in Molecular Biology, 2023 - mdpi.com
Cannabis and related compounds have created significant research interest as a promising
therapy in many disorders. However, the individual therapeutic effects of cannabinoids and …

Chemical warfare agents. Classes and targets

M Schwenk - Toxicology letters, 2018 - Elsevier
Synthetic toxic chemicals (toxicants) and biological poisons (toxins) have been developed
as chemical warfare agents in the last century. At the time of their initial consideration as …

In situ-Like Aerosol Inhalation Exposure for Cytotoxicity Assessment Using Airway-on-Chips Platforms

S Elias-Kirma, A Artzy-Schnirman, P Das… - … in Bioengineering and …, 2020 - frontiersin.org
Lung exposure to inhaled particulate matter (PM) is known to injure the airway epithelium
via inflammation, a phenomenon linked to increased levels of global morbidity and mortality …

Neurological susceptibility to environmental exposures: pathophysiological mechanisms in neurodegeneration and multiple chemical sensitivity

J Molot, M Sears, LM Marshall, RI Bray - Reviews on Environmental …, 2022 - degruyter.com
Abstract The World Health Organization lists air pollution as one of the top five risks for
developing chronic non-communicable disease, joining tobacco use, harmful use of alcohol …

[HTML][HTML] Multiple chemical sensitivity: it's time to catch up to the science

J Molot, M Sears, H Anisman - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Multiple chemical sensitivity (MCS) is a complex medical condition associated with low dose
chemical exposures. MCS is characterized by diverse features and common comorbidities …

Trp channels as cellular targets of particulate matter

A Milici, K Talavera - International Journal of Molecular Sciences, 2021 - mdpi.com
Particulate matter (PM) is constituted by particles with sizes in the nanometer to micrometer
scales. PM can be generated from natural sources such as sandstorms and wildfires, and …

Comparative effects of capsaicin in chronic obstructive pulmonary disease and asthma

MD Dumitrache, AS Jieanu… - Experimental and …, 2021 - spandidos-publications.com
Chronic obstructive pulmonary disease (COPD) and asthma are chronic respiratory
diseases with high prevalence and mortality that significantly alter the quality of life in …

Wood smoke particles stimulate MUC5AC overproduction by human bronchial epithelial cells through TRPA1 and EGFR signaling

TA Memon, ND Nguyen, KL Burrell… - Toxicological …, 2020 - academic.oup.com
Mucus hypersecretion is a pathological feature of acute inflammatory and chronic
obstructive pulmonary diseases. Exposure to air pollutants can be a cause of pathological …

Hydrogen Sulfide-Evoked Intracellular Ca2+ Signals in Primary Cultures of Metastatic Colorectal Cancer Cells

P Faris, F Ferulli, M Vismara, M Tanzi, S Negri… - Cancers, 2020 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the most common type of gastrointestinal
cancer and the third most predominant cancer in the world. CRC is potentially curable with …

Transient receptor potential vanilloid subtype 1: potential role in infection, susceptibility, symptoms and treatment of COVID-19

F Liviero, M Campisi, P Mason, S Pavanello - Frontiers in Medicine, 2021 - frontiersin.org
The battle against the new coronavirus that continues to kill millions of people will be still
long. Novel strategies are demanded to control infection, mitigate symptoms and treatment …