Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

The lubricated matter in body

H Yuan, W Cui - Progress in Materials Science, 2024 - Elsevier
Lubrication is everywhere in the body and essential for the correct operation of biological
systems when subjected to contact stress and wear. The body is like a continuously …

Involvement of aquaporin 5 in Sjögren's syndrome

C Chivasso, C D'Agostino, D Parisis, MS Soyfoo… - Autoimmunity …, 2023 - Elsevier
Sjögren's syndrome (SS) is a chronic autoimmune disease with the pathological hallmark of
lymphoplasmacytic infiltration of exocrine glands-more specifically salivary and lacrimal …

Mouth-watering results: Clinical need, current approaches, and future directions for salivary gland regeneration

C Rocchi, E Emmerson - Trends in molecular medicine, 2020 - cell.com
Permanent damage to the salivary glands and resulting hyposalivation and xerostomia have
a substantial impact on patient health, quality of life, and healthcare costs. Currently, patients …

Bioengineering in salivary gland regeneration

M Hajiabbas, C D'Agostino, J Simińska-Stanny… - Journal of biomedical …, 2022 - Springer
Salivary gland (SG) dysfunction impairs the life quality of many patients, such as patients
with radiation therapy for head and neck cancer and patients with Sjögren's syndrome …

Harnessing biomolecules for bioinspired dental biomaterials

NG Fischer, EA Münchow, C Tamerler… - Journal of Materials …, 2020 - pubs.rsc.org
Dental clinicians have relied for centuries on traditional dental materials (polymers,
ceramics, metals, and composites) to restore oral health and function to patients. Clinical …

Cancer therapy–related salivary dysfunction

C Paz, A Glassey, A Frick, S Sattar, NG Zaorsky… - The Journal of Clinical …, 2024 - jci.org
Salivary gland dysfunction is a common side effect of cancer treatments. Salivary function
plays key roles in critical daily activities. Consequently, changes in salivary function can …

Bioengineered Salivary Gland Microtissues─ A Review of 3D Cellular Models and their Applications

S Pillai, JG Munguia-Lopez, SD Tran - ACS Applied Bio Materials, 2024 - ACS Publications
Salivary glands (SGs) play a vital role in maintaining oral health through the production and
release of saliva. Injury to SGs can lead to gland hypofunction and a decrease in saliva …

CERE-120 prevents irradiation-induced hypofunction and restores immune homeostasis in porcine salivary glands

IMA Lombaert, VN Patel, CE Jones, DC Villier… - … Therapy-Methods & …, 2020 - cell.com
Salivary gland hypofunction causes significant morbidity and loss of quality of life for head
and neck cancer patients treated with radiotherapy. Preventing hypofunction is an unmet …