Collagen is the most abundant structural protein found in humans and mammals, particularly
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …

Since the 2010s, the demand for healthcare models has exceeded the prevailing resources
available due to the rapid increase in the aging population in China. However, a significant …

Being a bioactive material, hydroxyapatite (HAp) is regarded as one of the most attractive
ceramic biomaterials for bone and hard-tissue replacement and regeneration. Despite its …

Bone self-healing is limited and generally requires external intervention to augment bone
repair and regeneration. While traditional methods for repairing bone defects such as …

Collagen type I (Col-I) is unique due to its high biocompatibility in human tissue. Despite its
availability from various sources, Col-I naturally mimics the extracellular matrix (ECM) and …

In the recent years, a paradigm shift is taking place where metallic/synthetic implants and
tissue grafts are being replaced by tissue engineering approach. A well designed three …

This review focuses on the expanding role of marine collagen (MC)-based scaffolds for
biomedical applications. A scaffold—a three-dimensional (3D) structure fabricated from …

Bone defects cause significant socio-economic costs worldwide, while the clinical “gold
standard” of bone repair, the autologous bone graft, has limitations including limited graft …

Tissue engineering is considered one of the most important therapeutic strategies of
regenerative medicine. The main objective of these new technologies is the development of …

Recently, polymer based biomaterials are utilized in medical fields including surgical
sutures, drug delivery devices, tissue supports and implants for interior bone fixation …