This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Cells sense various in vivo mechanical stimuli, which initiate downstream signaling to
mechanical forces. While a body of evidences is presented on the impact of limited …

Atherosclerosis is an inflammatory disease that preferentially forms at hemodynamically
compromised regions of altered shear stress patterns. Endothelial cells (EC) and smooth …

Bone marrow mesenchymal stem cells (MSCs) have multi-differentiation capability. Their
endothelial cell (EC) oriented differentiation is the key to vasculogenesis, in which both …

Endothelial cell phenotypes markedly differ, depending upon function and vascular bed of
origin. Differences might account for specific susceptibility to pathological conditions. As …

Vascular functions are affected by wall shear stresses (WSS) applied on the endothelial
cells (EC), as well as by the interactions of the EC with the adjacent smooth muscle cells …

We have utilized serial analysis of gene expression (SAGE) to analyze the response of
human coronary artery endothelial cells (HCAECs) to laminar shear stress (LSS). Primary …

This review provides an overview of the effect of blood flow on endothelial cell (EC)
signalling pathways, applying microarray technologies to cultured cells, and in vivo studies …

To evaluate interactions between human endothelial cells (ECs) and smooth muscle cells
(SMCs) for the development of tissue-engineered vessels, we examined the adhesion and …

The modulation of vascular smooth muscle cell (VSMC) phenotype is an essential element
to fabricate engineered conduits of clinical relevance. In vivo, owing to their close proximity …