Targeting the microbiome-gut-brain axis for improving cognition in schizophrenia and major mood disorders: A narrative review

M Bioque, A González-Rodríguez… - Progress in Neuro …, 2021 - Elsevier
Cognitive impairment has been consistently found to be a core feature of serious mental
illnesses such as schizophrenia and major mood disorders (major depression and bipolar …

[HTML][HTML] Crosstalk between schizophrenia and metabolic syndrome: The role of oxytocinergic dysfunction

KK Goh, CYA Chen, TH Wu, CH Chen… - International journal of …, 2022 - mdpi.com
The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …

[HTML][HTML] Dysregulated Signaling at Postsynaptic Density: A Systematic Review and Translational Appraisal for the Pathophysiology, Clinics, and Antipsychotics' …

A de Bartolomeis, L Vellucci, G De Simone, B Mazza… - Cells, 2023 - mdpi.com
Emerging evidence from genomics, post-mortem, and preclinical studies point to a potential
dysregulation of molecular signaling at postsynaptic density (PSD) in schizophrenia …

[HTML][HTML] Sex-specific effects of polygenic risk for schizophrenia on lifespan cognitive functioning in healthy individuals

E Koch, L Nyberg, A Lundquist, S Pudas… - Translational …, 2021 - nature.com
Abstract Polygenic risk for schizophrenia has been associated with lower cognitive ability
and age-related cognitive change in healthy individuals. Despite well-established …

[PDF][PDF] Schizophrenia: epidemiology, causes, neurobiology, pathophysiology, and treatment

K Volkan - J Health Med Sci, 2020 - asianinstituteofresearch.org
Schizophrenia is a severe mental illness that has devastating consequences for those who
suffer from the disorder. The epidemiology of schizophrenia indicates that it occurs relatively …

Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness

C Makowski, H Wang, A Srinivasan… - Proceedings of the …, 2023 - National Acad Sciences
Human cortical expansion has occurred non-uniformly across the brain. We assessed the
genetic architecture of cortical global expansion and regionalization by comparing two sets …

Candidates for drug repurposing to address the cognitive symptoms in schizophrenia

E Koch, K Kauppi, CH Chen - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
In the protein-protein interactome, we have previously identified a significant overlap
between schizophrenia risk genes and genes associated with cognitive performance. Here …

[HTML][HTML] Therapeutic potential of morin: Special focus on cognitive dysfunction, diabetes mellitus and cancer

A Goyal, N Dubey, A Agrawal, A Verma… - … Modern Chinese Medicine, 2023 - Elsevier
Introduction Morin is a natural polyphenol that may be derived from the leaves, fruits, stems,
and branches of many different plants. It was first discovered in members of the Moraceae …

[HTML][HTML] Dissecting Schizophrenia Biology Using Pleiotropy with Cognitive Genomics

U Bhattacharyya, J John, T Lencz, M Lam - medRxiv, 2024 - ncbi.nlm.nih.gov
Given the increasingly large number of loci discovered by psychiatric GWAS, specification of
the key biological pathways underlying these loci has become a priority for the field. We …

Schizophrenia: Science, Psychoanalysis, and Culture

V Volkan, K Volkan - Schizophrenia, 2022 - torrossa.com
Kevin Volkan EdD, PhD, MPH is a founding faculty member and professor of psychology at
California State University Channel Islands, where he researches and teaches courses on …