Bicyclic peptides: paving the road for therapeutics of the future

S Ullrich, C Nitsche - Peptide Science, 2024 - Wiley Online Library
Bicyclic peptides have emerged as one of the driving forces within the constrained peptide
family. Due to their unique pharmaceutical attributes, peptide bicycles have garnered a …

An ultrasensitive ELISA to assay femtomolar level SARS-CoV-2 antigen based on specific peptide and tyramine signal amplification

J Liu, S Pang, M Wang, H Yu, P Ma, T Dong… - Sensors and Actuators B …, 2023 - Elsevier
The SARS-CoV-2 spreading rapidly has aroused catastrophic public healthcare issues and
economy crisis worldwide. It plays predominant role to rapidly and accurately diagnose the …

Practical tips and new trends in electrochemical biosensing of cancer-related extracellular vesicles

PS Sfragano, S Pillozzi, G Condorelli… - Analytical and …, 2023 - Springer
To tackle cancer and provide prompt diagnoses and prognoses, the constantly evolving
biosensing field is continuously on the lookout for novel markers that can be non-invasively …

Characterization of a ruthenium (II) complex in singlet oxygen-mediated photoelectrochemical sensing

M Verrucchi, GE Giacomazzo, PS Sfragano, S Laschi… - Langmuir, 2022 - ACS Publications
A water-soluble ruthenium (II) complex (L), capable of producing singlet oxygen (1O2) when
irradiated with visible light, was used to modify the surface of an indium–tin oxide (ITO) …

An Impedimetric Biosensing Strategy Based on BicyclicPeptides as Bioreceptors for Monitoring h-uPA Cancer Biomarkers

G Moro, L Ferrari, A Angelini, F Polo - Chemosensors, 2023 - mdpi.com
In the era of liquid biopsies, the reliable and cost-effective detection and screening of cancer
biomarkers has become of fundamental importance, thus paving the way for the …

Electrochemical sensing of target cells based on a peptide/single‐strand DNA probe

K Sugawara, K Takeda, H Kuramitz - Electroanalysis, 2023 - Wiley Online Library
To electrochemically measure human myeloid leukemia cells (K562 cells), we constructed a
probe consisting of peptide/single‐strand (ss) DNA. Ac‐H6Y4C with an acetylated N …