In the past 15 years, ambient ionization techniques have witnessed a significant incursion
into the field of mass spectrometry imaging, demonstrating their ability to provide …

Traditional Chinese medicine (TCM) is the key to unlock treasures of Chinese civilization.
TCM and its compound play a beneficial role in medical activities to cure diseases …

Over the last five years, mass spectrometry imaging (MSI) has made it possible to extract
spatially relevant information from numerous types of sample mediums including biofilms …

Imaging of lipids of whole-body specimens in two-dimensional (2D) analysis provides a
global picture of the lipid changes in lipid-disturbed diseases, enabling a better …

N-Linked glycans are structurally diverse polysaccharides that represent significant
biological relevance due to their involvement in disease progression and cancer. Due to …

Lipids play a crucial role in the growth and development of organisms. However, the lack of
effective chemical tools for lipid imaging has hindered a comprehensive understanding of …

Abstract Three-dimensional (3D) mass spectrometry imaging (MSI) has become a growing
frontier as it has the potential to provide a 3D representation of analytes in a label-free …

To better understand cell-to-cell heterogeneity, advanced analytical tools are in a growing
demand for elucidating chemical compositions of each cell within a population. However …

Zebrafish (Danio rerio) represent an effective model biological material for human disease
research, even for personalized precision medicine. Thus, it is necessary to fully …

Increasing the spatial resolution of a mass spectrometry imaging (MSI) method results in a
more defined heatmap of the spatial distribution of molecules across a sample, but it is also …