Food matrix and macronutrient digestion

E Capuano, AEM Janssen - Annual review of food science and …, 2021 - annualreviews.org
Food digestion may be regarded as a physiological interface between food and health.
During digestion, the food matrix is broken down and the component nutrients and bioactive …

Physiologically based modeling of food digestion and intestinal microbiota: state of the art and future challenges. An INFOGEST review

S Le Feunteun, A Al-Razaz, M Dekker… - Annual review of …, 2021 - annualreviews.org
This review focuses on modeling methodologies of the gastrointestinal tract during digestion
that have adopted a systems-view approach and, more particularly, on physiologically …

Model discrimination for drying and rehydration kinetics of freeze‐dried tomatoes

E Lopez‐Quiroga, V Prosapio, PJ Fryer… - Journal of Food …, 2020 - Wiley Online Library
The aim of this work is to investigate the effect of a highly interconnected porous
microstructure on the quality of rehydrated tomatoes by (a) designing a freeze‐dried cycle …

Development of a Gastric Simulation Model (GSM) incorporating gastric geometry and peristalsis for food digestion study

Y Li, L Fortner, F Kong - Food Research International, 2019 - Elsevier
There has been growing interest in developing in vitro gastrointestinal models as
alternatives to in vivo tests, which is challenging ethically and financially. An in vitro Gastric …

Comparison of hypoglycemic effects of polysaccharides from four legume species

GJ Wu, D Liu, YJ Wan, XJ Huang, SP Nie - Food Hydrocolloids, 2019 - Elsevier
Four legume polysaccharides were extracted from mung bean (MBP), azuki bean (ABP),
pea (PP) and cowpea (CPP) with obvious differences in molecular weight and …

An evolving view on food viscosity regulating gastric emptying

Y Jin, PJ Wilde, Y Hou, Y Wang, J Han… - Critical Reviews in Food …, 2023 - Taylor & Francis
Viscosity is a property of most foods. The consumption of the high-viscosity food is
associated with a variety of physiological responses, one of which is their ability to regulate …

Bridging the gap between food effects under clinical trial conditions and real life: modeling delayed gastric emptying of drug substances and gastric content volume …

F Winter, P Schick, W Weitschies - Molecular Pharmaceutics, 2022 - ACS Publications
Delayed gastric emptying is known to have a major impact on drug absorption. While the test
meal recommended by the FDA and EMA to study food effects represents a worst-case …

Achieving realistic gastric emptying curve in an advanced dynamic in vitro human digestion system: experiences with cheese—a difficult to empty material

Z Peng, P Wu, J Wang, D Dupont, O Menard… - Food & function, 2021 - pubs.rsc.org
Nowadays, in vitro digestion models have received growing interest in recent years to track
the digestive fate of foods in the gastrointestinal tract. A major challenge in the development …

Mathematical models of cystic fibrosis as a systemic disease

DV Olivença, JD Davis, CM Kumbale… - WIREs Mechanisms …, 2023 - Wiley Online Library
Cystic fibrosis (CF) is widely known as a disease of the lung, even though it is in truth a
systemic disease, whose symptoms typically manifest in gastrointestinal dysfunction first. CF …

Changing flows balance nutrient absorption and bacterial growth along the gut

A Codutti, J Cremer, K Alim - Physical Review Letters, 2022 - APS
Small intestine motility and its ensuing flow of luminal content impact both nutrient
absorption and bacterial growth. To explore this interdependence we introduce a …