UVA Radiation, DNA damage, and melanoma

SG Jin, F Padron, GP Pfeifer - ACS omega, 2022 - ACS Publications
Melanoma is a lethal type of skin tumor that has been linked with sunlight exposure chiefly in
fair-skinned human populations. Wavelengths from the sun that can reach the earth's …

[HTML][HTML] Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging

J Ma, Y Teng, Y Huang, X Tao, Y Fan - Frontiers in Pharmacology, 2022 - frontiersin.org
Photoaging is characterized by a chronic inflammatory response to UV light. One of the most
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …

Triterpenoid ursolic acid drives metabolic rewiring and epigenetic reprogramming in treatment/prevention of human prostate cancer

S Li, R Wu, L Wang, HC Dina Kuo… - Molecular …, 2022 - Wiley Online Library
Ursolic acid (UA) is a triterpenoid phytochemical with a strong anticancer effect. The
metabolic rewiring, epigenetic reprogramming, and chemopreventive effect of UA in prostate …

A high responsivity, high detectivity, and high response speed MSM UVB photodetector based on SnO 2 microwires

R Fu, X Jiang, Y Wang, D Xia, B Li, J Ma, H Xu, A Shen… - Nanoscale, 2023 - pubs.rsc.org
We report a high performance UVB photodetector with a metal–semiconductor–metal device
structure based on high crystal quality SnO2 microwires prepared by chemical vapor …

[HTML][HTML] UV radiation and its relation to DNA methylation in epidermal cells: A review

NFP de Oliveira, BF de Souza, M de Castro Coêlho - Epigenomes, 2020 - mdpi.com
DNA methylation is the most studied epigenetic mark, and it can be altered by environmental
factors. Among these factors, ultraviolet radiation (UV) is little explored within this context …

Tobacco carcinogen 4-[methyl (nitroso) amino]-1-(3-pyridinyl)-1-butanone (NNK) drives metabolic rewiring and epigenetic reprograming in A/J mice lung cancer …

RR Hudlikar, D Sargsyan, D Cheng, HCD Kuo… - …, 2022 - academic.oup.com
Early detection of biomarkers in lung cancer is one of the best preventive strategies.
Although many attempts have been made to understand the early events of lung …

UVB drives metabolic rewiring and epigenetic reprograming and protection by sulforaphane in human skin keratinocytes

S Li, HC Dina Kuo, L Wang, R Wu… - Chemical Research …, 2022 - ACS Publications
Sulforaphane (SFN) is a potent anticancer agent which could protect the skin from ultraviolet
(UV) radiation-induced insults. Currently, the metabolic rewiring and epigenetic …

Epigenome and transcriptome study of moringa isothiocyanate in mouse kidney mesangial cells induced by high glucose, a potential model for diabetic-induced …

S Li, W Li, R Wu, R Yin, D Sargsyan, I Raskin… - The AAPS journal, 2020 - Springer
Abstract Moringa isothiocyanate (MIC-1) is a bioactive constituent found abundantly in
Moringa oleifera which possesses antioxidant and anti-inflammation properties. However …

Epigenetics/epigenomics and prevention of early stages of cancer by isothiocyanates

R Hudlikar, L Wang, R Wu, S Li, R Peter… - Cancer Prevention …, 2021 - AACR
Cancer is a complex disease and cancer development takes 10–50 years involving
epigenetics. Evidence suggests that approximately 80% of human cancers are linked to …

Are TRPA1 and TRPV1 channel-mediated signalling cascades involved in UVB radiation-induced sunburn?

C Camponogara, SM Oliveira - Environmental Toxicology and …, 2022 - Elsevier
Burn injuries are underappreciated injuries associated with substantial morbidity and
mortality. Overexposure to ultraviolet (UV) radiation has dramatic clinical effects in humans …