Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 1: definitions, diagnosis, extra-intestinal manifestations …

F Magro, P Gionchetti, R Eliakim… - Journal of Crohn's …, 2017 - academic.oup.com
1.2. Definitions Ulcerative colitis [UC] is a chronic inflammatory condition that causes
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …

Systematic review with meta‐analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis …

A Cholapranee, GS Hazlewood… - Alimentary …, 2017 - Wiley Online Library
Background Mucosal healing is an important therapeutic endpoint in the management of
Crohn's disease (CD) and ulcerative colitis (UC). Limited data exist regarding the …

PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting …

X Gui, A Bazarova, R Del Amor, M Vieth, G De Hertogh… - Gut, 2022 - gut.bmj.com
Histological remission is evolving as an important treatment target in UC. We aimed to
develop a simple histological index, aligned to endoscopy, correlated with clinical outcomes …

European evidence based consensus for endoscopy in inflammatory bowel disease

V Annese, M Daperno, MD Rutter… - Journal of Crohn's …, 2013 - academic.oup.com
Endoscopy plays an essential role in the diagnosis, management, prognosis, and
surveillance of inflammatory bowel disease (IBD), but surprisingly there are few available …

Fecal transplantation for treatment of inflammatory bowel disease

A Imdad, NG Pandit, M Zaman… - Cochrane Database …, 2023 - cochranelibrary.com
Background Inflammatory bowel disease (IBD) is a chronic, relapsing disease of the
gastrointestinal (GI) tract that is thought to be associated with a complex interplay between …

Beyond endoscopic mucosal healing in UC: histological remission better predicts corticosteroid use and hospitalisation over 6 years of follow-up

RV Bryant, DC Burger, J Delo, AJ Walsh, S Thomas… - Gut, 2016 - gut.bmj.com
Background Endoscopic mucosal healing is an established treatment target for UC, yet the
value of achieving histological remission remains unclear. Aims To evaluate histological …

Clinical disease activity, C-reactive protein normalisation and mucosal healing in Crohn's disease in the SONIC trial

L Peyrin-Biroulet, W Reinisch, JF Colombel… - Gut, 2014 - gut.bmj.com
Background and aims The Crohn's Disease Activity Index (CDAI) has been criticised due to
heavy weighting on subjective clinical symptoms. C-reactive protein (CRP) and endoscopic …

ECCO position paper: harmonization of the approach to ulcerative colitis histopathology

F Magro, G Doherty, L Peyrin-Biroulet… - Journal of Crohn's …, 2020 - academic.oup.com
Currently, the main targets of drug therapy for ulcerative colitis [UC] are endoscopic and
clinical remission. However, there is active discussion about the additional advantages of …

Systematic review: histological remission in inflammatory bowel disease. Is 'complete'remission the new treatment paradigm? An IOIBD initiative

RV Bryant, S Winer, T SPL… - Journal of Crohn's and …, 2014 - academic.oup.com
Background and aims: Advances in the medical management of inflammatory bowel
disease (IBD) have altered treatment targets. Endoscopic mucosal healing is associated …

European Crohn's and Colitis Organisation topical review on treatment withdrawal ['exit strategies'] in inflammatory bowel disease

G Doherty, KH Katsanos, J Burisch… - Journal of Crohn's …, 2018 - academic.oup.com
Clinically effective therapies now exist for remission maintenance in both ulcerative colitis
[UC] and Crohn's Disease [CD]. For each major class of IBD medications [5 …