Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

Polycyclic aromatic hydrocarbons (PAHs) are a class of common persistent environmental
pollutants found in water, air, soil, and plants and can be released by natural sources …

Evidence indicates that ethanol-induced intestinal barrier dysfunction and subsequent
endotoxemia plays a key role in the pathogenesis of alcoholic liver disease. Recently, it has …

Abstract Background Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous chemicals
with mechanisms of toxicity that include endocrine disruption. We examined associations of …

Normal pregnancy is associated with uterine relaxation to accommodate the stretch imposed
by the growing fetus; however, the mechanisms underlying the relationship between …

We have previously shown that butyrate, a short-chain fatty acid fiber fermentation product,
induces colonocyte apoptosis via a nonmitochondrial, Fas-mediated, extrinsic pathway …

Understanding the basis for the control of myometrial contractant and relaxant signaling
pathways is important to understanding how to manage myometrial contractions. Signaling …

Quiescence of myometrium contractile activity allows uterine expansion to accommodate the
growing fetus and prevents preterm labor particularly during excessive uterine stretch in …

Activin is a pleiotropic growth factor with a broad pattern of tissue distribution that includes
reproductive tissues. Although direct actions of activin have been described in gonadal and …

Context: Our previous study has demonstrated that CRH has differential effects on human
uterine contractility before and after onset of labor. Intracellular Ca2+ concentration ([Ca2+] …