Vaccination is one of the most successful and cost‐effective prophylactic measures against
diseases, especially infectious diseases including smallpox and polio. However, the …

Background We previously identified PRAME as a biomarker for metastatic risk in Class 1
uveal melanomas. In this study, we sought to define a threshold value for positive PRAME …

Loss of tumor suppressor proteins, such as the retinoblastoma protein (Rb), results in tumor
progression and metastasis. Metastasis is facilitated by low oxygen availability within the …

Primary glioma, as well as secondary metastases, provide significant treatment challenges.
An understanding of the biological underpinnings of glioma is likely to provide new …

Chromatin immunoprecipitation (ChIP) exploits the specific interactions between DNA and
DNA-associated proteins. It can be used to examine a wide range of experimental …

The effects of the organic flame retardant 1, 2‐Dibromo‐4‐(1, 2‐dibromoethyl) cyclohexane
(TBECH) on androgen receptor target gene expression were examined in the human …

Hypoxia modulates actin organization via multiple pathways. Analyzing the effect of hypoxia
on the biophysical properties of cancer cells is beneficial for studying modulatory signalling …

Introduction: TRIP11 is a multifunctional protein localizing either to Golgi apparatus, acting
as a golgin, or in the nucleus, acting as coactivator of transcription mediated by thyroid …

We know that different types of cancers usually have different responses to the same
treatment. Therefore, it is important to understand the similarities and differences across …

Cancer is a complex disease, requiring specific treatments for each type. Triple-negative
breast cancer (TNBC) is the most aggressive form of human breast cancer; however, it lacks …