Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …

The small ubiquitin-related modifier SUMO posttranslationally modifies many proteins with
roles in diverse processes including regulation of transcription, chromatin structure, and …

Ubiquitin is important for nearly every aspect of cellular physiology. All viruses rely
extensively on host machinery for replication; therefore, it is not surprising that viruses …

Epstein–Barr virus (EBV) is associated with a still growing spectrum of clinical disorders,
ranging from acute and chronic inflammatory diseases to lymphoid and epithelial …

ABSTRACT STAT3 and STAT5 are constitutively activated and nuclear in nasopharyngeal
carcinoma (NPC) cells. In normal signaling, STATs are only transiently activated. To …

The Epstein-Barr virus (EBV) is the first identified human virus with a proven association with
the pathogenesis of cancer. To maintain the integrity of the viral genome and to “get out” of …

Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA3C) and EBNA3A are each essential for
EBV conversion of primary human B lymphocytes into continuously proliferating lymphoblast …

To elucidate the mechanisms by which Epstein-Barr virus (EBV) latency III gene expression
transforms primary B lymphocytes to lymphoblastoid cell lines (LCLs), the associated …

Epstein–Barr virus (EBV) is an oncogenic human herpesvirus in the γ-herpesvirinae
subfamily that contains a 170–180 kb double-stranded DNA genome. In vivo, EBV …