A view on uterine leiomyoma genesis through the prism of genetic, epigenetic and cellular heterogeneity

AS Koltsova, OA Efimova, AA Pendina - International Journal of …, 2023 - mdpi.com
Uterine leiomyomas (ULs), frequent benign tumours of the female reproductive tract, are
associated with a range of symptoms and significant morbidity. Despite extensive research …

Telocytes in fibrosis diseases: From current findings to future clinical perspectives

X Wei, T Chen, X Yang - Cell Transplantation, 2022 - journals.sagepub.com
Telocytes (TCs), a distinct type of interstitial (stromal) cells, have been discovered in many
organs of human and mammal animals. TCs, which have unique morphological …

Roles of pulmonary telocytes in airway epithelia to benefit experimental acute lung injury through production of telocyte-driven mediators and exosomes

L Tang, D Song, R Qi, B Zhu, X Wang - Cell Biology and Toxicology, 2022 - Springer
Abstract Background Telocytes (TCs) are experimentally evidenced as an alternative of cell
therapies for organ tissue injury and repair. The aims of the present studies are to explore …

Telocytes enhances M1 differentiation and phagocytosis while inhibits mitochondria-mediated apoptosis via activation of NF-κB in macrophages

YL Huang, FL Zhang, XL Tang… - Cell …, 2021 - journals.sagepub.com
Telocytes (TCs), which are a recently discovered interstitial cell type present in various
organs and tissues, perform multiple biological functions and participate in extensive …

Telocytes in the tumor microenvironment

V Aleksandrovych, K Gil - Tumor Microenvironment: Novel Concepts, 2021 - Springer
There are several theories explaining the communication between cells in the context of
tumor development. Over the years, interactions between normal and transformed cells have …

Telocytes: new connecting devices in the stromal space of organs

D Cretoiu, MG Vannucchi, Y Bei… - Innovations in cell …, 2020 - books.google.com
Telocytes (TCs) represent a new type of interstitial cells, and were discovered by Prof.
Popescu and his collaborators from Bucharest in 2005, and described as Interstitial Cajal …

Pathophysiological implications of interstitial Cajal-like cells (ICC-like) in uterus: a comparative study with gastrointestinal ICCs

L López-Pingarrón, H Almeida… - Current Issues in …, 2023 - mdpi.com
The main function of interstitial cells of Cajal (ICCs) is to regulate gastrointestinal peristalsis
by acting as a “pacemaker” cell by generating spontaneous slow electrical waves. In 2005 …

Telocytes and endometriosis

T Xu, H Zhang, Z Zhu - Archives of Gynecology and Obstetrics, 2023 - Springer
Endometriosis involving the presence and growth of glands and stroma outside the uterine
cavity is a common, inflammatory, benign gynecologic disease. Nevertheless, no single …

Telocytes in the architecture of uterine fibroids

V Aleksandrovych, A Pasternak, K Gil - Folia medica Cracoviensia, 2019 - ruj.uj.edu.pl
Knowledge of uterine fibroids has existed since the time of Hippocrates. However, there are
still wide gaps in the understanding of its pathogenesis. No single theory explains the …

Oviductal telocytes in patients with uterine myoma

V Aleksandrovych, A Wrona, T Bereza, K Pityński, K Gil - Biomedicines, 2021 - mdpi.com
Tubal factor infertility occurs in 30–35% of infertile pairs and may be caused by impaired
muscular contractility and ciliary beating as well as immunological imbalance and chronic …