Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma

MA Abd-Elmawla, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …

Exosome-derived noncoding RNAs: Function, mechanism, and application in tumor angiogenesis

K Yang, Q Zhou, B Qiao, B Shao, S Hu, G Wang… - … Therapy-Nucleic Acids, 2022 - cell.com
Exosomes are extracellular vesicles released by various cell types that perform various
biological functions, mainly mediating communication between different cells, especially …

Tumor immune microenvironment and genetic alterations in mesothelioma

S Hiltbrunner, L Mannarino, MB Kirschner… - Frontiers in …, 2021 - frontiersin.org
Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up to
80% of the MPM cases are linked to asbestos exposure. Even though its use has been …

Exosomal miR-130b-3p targets SIK1 to inhibit medulloblastoma tumorigenesis

S Huang, P Xue, X Han, C Zhang, L Yang, L Liu… - Cell Death & …, 2020 - nature.com
Exosomes are an important carrier for cell communication. miRNAs in exosomes are
potential biomarkers and therapeutic targets in different types of cancer. However, the role of …

Molecular biomarkers in sinonasal cancers: new frontiers in diagnosis and treatment

M Turri-Zanoni, G Gravante, P Castelnuovo - Current Oncology Reports, 2022 - Springer
Abstract Purpose of Review Sinonasal tumors are rare and heterogeneous diseases which
pose challenges in diagnosis and treatment. Despite significant progress made in surgical …

Up-regulation of long noncoding RNA MINCR promotes non-small cell of lung cancer growth by negatively regulating miR-126/SLC7A5 axis

J Wang, M Ding, H Zhu, Y Cao, W Zhao - Biochemical and biophysical …, 2019 - Elsevier
A growing body of evidence suggests that MYC induced long noncoding RNA (MINCR) is
involved in the initiation and progression of various tumors. However, little is known about …

Integrative network analysis of differentially methylated and expressed genes for biomarker identification in leukemia

R Sanchez, SA Mackenzie - Scientific reports, 2020 - nature.com
Genome-wide DNA methylation and gene expression are commonly altered in pediatric
acute lymphoblastic leukemia (PALL). Integrated network analysis of cytosine methylation …

Unlocking the potential of exosomes in cancer research: A paradigm shift in diagnosis, treatment, and prevention

S Khoushab, MH Aghmiuni, N Esfandiari… - … -Research and Practice, 2024 - Elsevier
Exosomes, which are tiny particles released by cells, have the ability to transport various
molecules, including proteins, lipids, and genetic material containing non-coding RNAs …

miRNAs emerge as circulating biomarkers of post-myocardial infarction heart failure

MS Cruz, AMG da Silva, KSC de Souza… - Heart Failure …, 2020 - Springer
Heart failure (HF) is a clinical syndrome that involves structural changes in the heart, leading
to a decrease in cardiac output, mainly caused by myocardial infarction (MI), which is the …

MiRNome analysis identifying miR‐205 and miR‐449a as biomarkers of disease progression in intestinal‐type sinonasal adenocarcinoma

M Re, M Tomasetti, F Monaco, M Amati, C Rubini… - Head & …, 2022 - Wiley Online Library
Background Patients with intestinal‐type sinonasal adenocarcinoma (ITAC) have an
unfavorable prognosis, and new diagnostic and therapeutic approaches are needed to …