The recent proliferation of cryo-electron tomography (cryo-ET) techniques has led to the cryo-
ET resolution revolution. Meanwhile, significant efforts have been made to improve the …

We present a new approach for macromolecular structure determination from multiple
particles in electron cryo-tomography (cryo-ET) data sets. Whereas existing subtomogram …

Advances in cryo-electron tomography (cryo-ET) have produced new opportunities to
visualize the structures of dynamic macromolecules in native cellular environments. While …

Electron tomography of frozen, hydrated samples allows structure determination of
macromolecular complexes that are embedded in complex environments. Provided that the …

Cryoelectron tomography directly visualizes heterogeneous macromolecular structures in
their native and complex cellular environments. However, existing computer-assisted …

Structures of macromolecules in their native state provide unique unambiguous insights into
their functions. Cryo-electron tomography combined with subtomogram averaging …

Methods of transmission electron microscopy (TEM) are typically used to resolve structures
of vitrified biological specimens using both single particle analysis (SPA) and tomographic …

Cryo electron tomography (cryo-ET) allows observing macromolecular complexes in their
native environment. The common routine of subtomogram averaging (STA) allows obtaining …

MemBrain v2 is a deep learning-enabled program aimed at the efficient analysis of
membranes in cryo-electron tomography (cryo-ET). The final v2 release of MemBrain will …

Cryo-electron tomography can uniquely probe the native cellular environment for
macromolecular structures. Tomograms feature complex data with densities of diverse …