The placebo effect has often been considered a nuisance in basic and particularly clinical
research. This view has gradually changed in recent years due to deeper insight into the …

Placebo response in clinical trials of antidepressant medications is substantial and has been
increasing. High placebo response rates hamper efforts to detect signals of efficacy for new …

This randomized controlled trial was performed to investigate whether placebo effects in
chronic low back pain could be harnessed ethically by adding open-label placebo (OLP) …

Depression is a global health problem requiring treatment innovation. Targeting neglected
cognitive aspects may provide a useful route. We tested a cognitive-training paradigm using …

Objective: The primary aim of this study was to assess the overall effectiveness of and
dropout from individual and group outpatient cognitive behavioral therapy (CBT) for adults …

In psychiatry, comparative analyses of therapeutic options and the aggregation of data from
clinical trials across different therapeutic approaches play an important role in clinical …

There is a growing literature exploring the placebo response within specific mental
disorders, but no overarching quantitative synthesis of this research has analyzed evidence …

There is urgent need for improvement in community-based mental health care for children
and families. Multiple studies have documented serious limitations in the effectiveness of …

Of more than 155,000 PubMed citations found with the search term “placebo,” only~ 9,000
(5.8%) included the terms “children” or “adolescents.” When all these papers were screened …

Antidepressants are currently the treatment of choice for major depressive disorder (MDD).
Nevertheless, a high percentage of patients do not respond to a first-line antidepressant …