Importance—Primary central nervous system (CNS) germ cell tumors (GCT) are a
heterogeneous group of tumors that are still poorly understood. In North America, GCTs …

Radiotherapy plays an important role in the management of childhood cancer, with the
primary aim of achieving the highest likelihood of cure with the lowest risk of radiation …

Objective To develop a consensus guideline for craniospinal target volume (TV) delineation
in children and young adults participating in SIOPE studies in the era of high-precision …

Cancer is a major cause of childhood death, with central nervous system (CNS) neoplasms
being the second most common pediatric malignancy, following hematological cancer …

Primary central nervous system (CNS) germ cell tumors (GCTs) are a heterogeneous group
of lesions that account for 0.5% of all primary brain and CNS tumors, occurring at an …

Intracranial germ cell tumours (icGCTs) are uncommon tumours occurring in children and
young adults. They are usually segregated into germinomas and non-germinomatous …

Background Patients presenting with synchronous bifocal intracranial tumors (masses in the
pineal and neurohypophyseal region), detectable human chorionic gonadotropin (hCG) …

Intracranial germ cell tumors (iGCTs) are a heterogeneous group of tumors with peculiar
characteristics clearly distinguished from other brain tumors of neuroepithelial origin …

Central neurocytoma (CN) typically presents as an intraventricular mass causing obstructive
hydrocephalus. The first line of treatment is surgical resection with adjuvant conventional …

The role of diffusion weighted imaging and apparent diffusion coefficient in intracranial germ
cell tumors has not been fully elucidated. The aim of this study was to evaluate whether the …