Artificial intelligence in surveillance, diagnosis, drug discovery and vaccine development against COVID-19

G Arora, J Joshi, RS Mandal, N Shrivastava, R Virmani… - Pathogens, 2021 - mdpi.com
As of August 6th, 2021, the World Health Organization has notified 200.8 million laboratory-
confirmed infections and 4.26 million deaths from COVID-19, making it the worst pandemic …

An overview of in silico vaccine design against different pathogens and cancer

K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …

Immunoinformatic-based design of immune-boosting multiepitope subunit vaccines against monkeypox virus and validation through molecular dynamics and immune …

M Suleman, F Rashid, S Ali, H Sher, S Luo… - Frontiers in …, 2022 - frontiersin.org
Monkeypox virus is the causative agent of monkeypox disease, belonging to an
orthopoxvirus genus, with a disease pattern similar to that of smallpox. The number of …

The relevance of bioinformatics applications in the discovery of vaccine candidates and potential drugs for COVID-19 treatment

OS Chukwudozie, VC Duru… - … and Biology Insights, 2021 - journals.sagepub.com
The application of bioinformatics to vaccine research and drug discovery has never been so
essential in the fight against infectious diseases. The greatest combat of the 21st century …

Advances of reverse vaccinology for mRNA vaccine design against SARS-CoV-2: a review of methods and tools

MK da Silva, DMO Campos, S Akash, S Akter, LC Yee… - Viruses, 2023 - mdpi.com
mRNA vaccines are a new class of vaccine that can induce potent and specific immune
responses against various pathogens. However, the design of mRNA vaccines requires the …

An overview of progress from empirical to rational design in modern vaccine development, with an emphasis on computational tools and immunoinformatics …

S Soleymani, A Tavassoli, MR Housaindokht - Computers in biology and …, 2022 - Elsevier
Vaccination remains the most effective strategy for preventing and controlling infectious
diseases. Numerous conventional vaccines, especially live attenuated, inactivated (killed) …

Infectious disease mRNA vaccines and a review on epitope prediction for vaccine design

X Cai, JJ Li, T Liu, O Brian, J Li - Briefings in Functional …, 2021 - academic.oup.com
Messenger RNA (mRNA) vaccines have recently emerged as a new type of vaccine
technology, showing strong potential to combat the COVID-19 pandemic. In addition to …

A Structural View at Vaccine Development against M. tuberculosis

M Romano, F Squeglia, E Kramarska, G Barra… - Cells, 2023 - mdpi.com
Tuberculosis (TB) is still the leading global cause of death from an infectious bacterial agent.
Limiting tuberculosis epidemic spread is therefore an urgent global public health priority. As …

[HTML][HTML] Staphylococcus aureus vaccine strategy: promise and challenges

U Chand, P Priyambada, PK Kushawaha - Microbiological Research, 2023 - Elsevier
Staphylococcus aureus (S. aureus) is a leading and crucial infectious threat to global public
health due to the widespread emergence of antibiotic-resistant strains such as Methicillin …

Toward rational vaccine engineering

YL Vishweshwaraiah, NV Dokholyan - Advanced drug delivery reviews, 2022 - Elsevier
Technological revolutions in several fields have pushed the boundaries of vaccine design
and provided new avenues for vaccine development. Next-generation vaccine platforms …