2024 Recommendations on the Optimal Use of Lipid-Lowering Therapy in Established Atherosclerotic Cardiovascular Disease and Following Acute Coronary …

M Banach, Ž Reiner, S Surma, G Bajraktari… - Drugs, 2024 - Springer
Atherosclerotic cardiovascular disease (ASCVD) and consequent acute coronary
syndromes (ACS) are substantial contributors to morbidity and mortality across Europe …

Whether and Why Do We Need a Vaccine Against Atherosclerosis? Can We Expect It Anytime Soon?

S Surma, A Sahebkar, M Banach - Current atherosclerosis reports, 2024 - Springer
Abstract Purpose of Review Atherosclerotic cardiovascular disease (ASCVD) is a leading
cause of premature death. Lipid disorders, particularly elevated serum low-density …

[HTML][HTML] 2023: The year in cardiovascular disease–the year of new and prospective lipid lowering therapies. Can we render dyslipidemia a rare disease by 2024?

M Banach, S Surma, PP Toth - Archives of Medical Science: AMS, 2023 - ncbi.nlm.nih.gov
In 2023 there are still even 75% of patients over the target of low-density lipoprotein
cholesterol (LDL-C), and hypercholesterolemia is the most common and the worst monitored …

Application of proteomics for novel drug discovery and risk prediction optimisation in stroke and myocardial infarction: a review of in-human studies

RJ Webb, M Al-Asmakh, M Banach, M Mazidi - Drug Discovery Today, 2024 - Elsevier
The use of proteomics in human studies investigating stroke and myocardial infarction (MI)
has been increasing, prompting a review of the literature. This revealed proteinaceous …

Zilebesiran—the first siRNA-based drug in hypertensiology: why is it needed, and will it change the treatment approach of hypertension?

S Surma, S Oparil - Arterial Hypertension, 2024 - journals.viamedica.pl
Arterial hypertension is the most common cardiovascular risk factor in the world. The
prevalence of hypertension has doubled over the last 30 years. Despite the availability of …

Nutrition, nutraceuticals and bioactive compounds in the prevention and fight against inflammation

S Surma, A Sahebkar, M Banach - Nutrients, 2023 - mdpi.com
SARS-CoV-2—severe acute respiratory syndrome coronavirus 2; MetS—metabolic
syndrome; DMT2—diabetes mellitus type 2; MAFLD—metabolic-associated fatty liver …

Position paper of the Polish Expert Group on the use of pitavastatin in the treatment of lipid disorders in Poland endorsed by the Polish Lipid Association

M Banach, S Surma, A Kapłon-Cieślicka, P Mitkowski… - Lekarz POZ, 2023 - termedia.pl
Position paper of the Polish expert group on the use of pitavastatin in the treatment of lipid
disorders in Poland endorsed by the Polish Lipid Association Journals Advances in Dermatology …

[HTML][HTML] Risk of adverse cardiovascular events based on common genetic variants in 8-year follow-up of the LIPIDOGEN2015 population using the polygenic risk …

M Banach, M Fronczek, T Osadnik… - Archives of Medical …, 2024 - pmc.ncbi.nlm.nih.gov
Introduction Classical risk factors such as hypertension, hypercholesterolemia, pre-diabetes,
diabetes and obesity can predict adverse cardiovascular events, but they are less prognostic …

Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia

Q Fang, X Lu, Y Zhu, X Lv, F Yu, X Ma, B Liu… - Cell Reports …, 2024 - cell.com
Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the low-density lipoprotein
receptor (LDLR) and mediates its internalization and degradation, resulting in an increase in …

Celebrating the 90th birthday of the scientist who discovered statins: Akira Endō

S Surma, DP Mikhailidis, M Banach - 2024 - academic.oup.com
In 1971, Dr Akira Endō (Figure 1A), working at the Sankyo company in Tokyo, speculated
that fungi not only contained antibiotics but also inhibitors of other processes, such as …