Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …

Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

The blood–brain barrier (BBB) is a critical regulator of CNS homeostasis. It possesses
physical and biochemical characteristics (ie tight junction protein complexes, transporters) …

The pro-inflammatory immune response driven by microglia is a key contributor to the
pathogenesis of several neurodegenerative diseases. Though the research of microglia …

There is growing evidence that excessive microglial phagocytosis of neurons and synapses
contributes to multiple brain pathologies. RNA‐seq and genome‐wide association (GWAS) …

Microglia are critical nervous system‐specific immune cells serving as tissue‐resident
macrophages influencing brain development, maintenance of the neural environment …

One of the most striking hallmarks shared by various neurodegenerative diseases, including
Parkinson's disease, Alzheimer's disease (AD), and amyotrophic lateral sclerosis, is …

As the major cellular component of the innate immune system in the central nervous system
(CNS) and the first line of defense whenever injury or disease occurs, microglia play a …

Macrophages are important players in the fight against viral, bacterial, fungal and parasitic
infections. From a resting state they may undertake two activation pathways, the classical …