Aging is associated with chronic systemic inflammation, which contributes to the
development of many age-related diseases, including vascular disease. The world's …

Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects
approximately 24% to 40% of the population of the Western world. In addition to its well …

Aging compromises the repair and regrowth of brain vasculature and white matter during
stroke recovery, but the underlying mechanisms remain elusive. To understand how aging …

B cells, also known as B lymphocytes or lymphoid lineage cells, are a historically
understudied cell population with regard to brain-related injuries and diseases. However, an …

In both acute and chronic diseases, functional differences in host immune responses arise
from a multitude of intrinsic and extrinsic factors. Two of the most important factors affecting …

Acute injury to the central nervous system (CNS) remains a complex and challenging clinical
need. CNS injury initiates a dynamic neuroinflammatory response, mediated by both …

Ischemic stroke is one of the world's leading causes of death and disability. It has been
established that gender differences in stroke outcomes prevail, and the immune response …

Purpose The prognosis following a hemorrhagic stroke is usually extremely poor. Rating
scales have been developed to predict the outcomes of patients with intracerebral …

Abstract Changes in the immune system associated with ageing are known as
immunosenescence. This is characterised by a decline in immune response, chronic …

Background After ischemic stroke (IS), peripheral leukocytes infiltrate the damaged region
and modulate the response to injury. Peripheral blood cells display distinctive gene …