Abstract Treatment of bone and joint infections can be challenging as antibiotics should
penetrate through the rigid bone structure and into the synovial space. Several …

Introduction Fosfomycin is a wide spectrum bactericidal antibiotic with a unique mode of
action, low toxicity, and good penetration in tissues with deep-seated infections, including …

Scaffolds grafting combined with local delivery of antibiotics at the injury site may promote
bone regeneration along with prevention of infections. In this work, a processing strategy …

Osteomyelitis, or bone infection, is often induced by antibiotic resistant Staphylococcus
aureus strains of bacteria. Although debridement and long-term administration of antibiotics …

Results Mean age was 52.5±18.3 years and 233 (67.7%) were male. Main osteomyelitis
types were post-surgical (31.1%), post-traumatic (26.2%) and hematogenous (23%). Tibia …

Phage therapy offers a potential alternate strategy for the treatment of peri-prosthetic joint
infection (PJI), particularly where limited effective antibiotics are available. We undertook …

Background Vancomycin (VAN) is effective in inhibiting inflammatory reactions in chronic
osteomyelitis (CO), while nano-hydroxyapatite (nHA) can effectively address the poor …

Dalbavancin is a new semisynthetic lipoglycopeptide with improved antimicrobial activity
against various gram-positive pathogens. It demonstrates an extensive plasma half-life …

Osteoarticular infections include septic arthritis and osteomyelitis, with Gram-positive
microorganisms isolated most frequently. In recent years, there has been an increase in the …

The aim of this study was to evaluate the combination of daptomycin and fosfomycin in
experimental chronic implant-associated osteomyelitis due to methicillin-resistant …