Delivery of nucleic acid based genome editing platforms via lipid nanoparticles: Clinical applications
R Masarwy, L Stotsky-Oterin, A Elisha… - Advanced Drug Delivery …, 2024 - Elsevier
CRISPR/Cas technology presents a promising approach for treating a wide range of
diseases, including cancer and genetic disorders. Despite its potential, the translation of …
diseases, including cancer and genetic disorders. Despite its potential, the translation of …
In vivo liver targeted genome editing as therapeutic approach: progresses and challenges
The liver is an essential organ of the body that performs several vital functions, including the
metabolism of biomolecules, foreign substances, and toxins, and the production of plasma …
metabolism of biomolecules, foreign substances, and toxins, and the production of plasma …
Recent Therapeutic Gene Editing Applications to Genetic Disorders
E Deneault - Current Issues in Molecular Biology, 2024 - mdpi.com
Recent years have witnessed unprecedented progress in therapeutic gene editing,
revolutionizing the approach to treating genetic disorders. In this comprehensive review, we …
revolutionizing the approach to treating genetic disorders. In this comprehensive review, we …
In vivo LNP-CRISPR Approaches for the Treatment of Hemophilia
Hemophilia is a genetic disorder that is caused by mutations in coagulation factor VIII
(hemophilia A) or IX (hemophilia B) genes resulting in blood clotting disorders. Despite …
(hemophilia A) or IX (hemophilia B) genes resulting in blood clotting disorders. Despite …